1. Gotu Kola Extract Overview
Gotu kola extract, also known as centella asiatica extract, provides major benefits to the skin, due to the exits of various active components. The active ingredients in gotu kola extract have been isolated in 1948. They are a series of triterpenoids, including saponins (asiatic acid and madecassic acid), as well as their storage form glucosides (asiaticoside, madecassoside). In addition, gotu kola extract contains polyphenols and flavonoids. It precisely because of these chemical components has a variety of effects. The mechanism of action is mainly achieved as the following.
- Promote the growth of skin fibroblasts
- Promote skin collagen synthesis
- Repair broken elastic fibers
- Promote the regeneration of cells and tissues
- Soothe and inhibit inflammation
In short, the active ingredients in gotu kola extract can achieve great value in skin care products. Gotu kola extract’s skin care effects are mainly shown in improving the barrier function of the epidermis, promoting skin collagen synthesis, soothing skin inflammation, reducing acne as well as stretch marks.
Product Name | CAS Number | INCI Name | ||
Gotu Kola Extract | 84696-21-9 | CENTELLA ASIATICA EXTRACT | ||
Product ID | Specification | Appearance | Soluble in | |
PMQD0801 | 70% Total Triterpenes
(Asiaticoside + Madecassoside + Asiaticoside B) |
Pale yellow to off white powder | Water, alcohol | |
PMQD0802 | 10% Total Triterpenes
(Asiaticoside + Madecassoside + Asiaticoside B) |
Off white powder | Water | |
PMQD0806 | 95% Asiaticoside | White powder | Alcohol | |
PMQD0803 | 90% Madecassoside
(Madecassoside + Asiaticoside B) |
White powder | Water | |
PMQD0805 | 36-44% Asiaticoside (HPLC), 54-66% Asiatic acid + Madecassic acid (titration) | Off white powder | Alcohol |
2. Gotu Kola Extract Source
Gotu kola is native to India; it is fond of moist river banks, swamps and grasslands, widely growing in tropical and subtropical areas. Earlier, in China and India, gotu kola, as a kind of herbal medicine, was mainly used to treat wound and leprosy. With the development of science, gotu kola is increasingly applied in other fields, especially in cosmetics industry.
3. Gotu Kola Extract Manufacturer Specifications
95% Gotu Kola Extract (Asiaticoside) Manufacturer Specification
Items | Specifications |
Assay | Asiaticoside ≥95.0% HPLC |
Color | Off-white powder |
Physical Characteristics | |
Granule size | 100% pass 80 mesh |
Loss on drying | ≤5.00% |
Sulphated ash | ≤1.00% |
Heavy Metals | |
Heavy Metals | ≤10ppm |
Cd | ≤1ppm |
Hg | ≤0.1ppm |
As | ≤1ppm |
Pb | ≤3ppm |
Microbiological Tests | |
Total plate count | ≤1000cfu/g |
Yeast & molds | ≤100cfu/g |
Salmonella | Negative |
E-Coli | Negative |
10% Gotu Kola Extract (Asiaticoside+Madecassoside+Asiaticoside B) Manufacturer Specification
Items | Specifications |
Assay | Total triterpenes ≥10.0%
(Asiaticoside +Madecassoside+Asiaticoside B) |
Color | Off-white powder |
TLC | Conforms |
Physical Characteristics | |
Loss on drying | ≤5.00% |
Sulphated ash | ≤1.00% |
Granule size | 98% pass 100 mesh |
Heavy Metals | |
Heavy Metals | ≤20 ppm |
Cd | ≤0.3ppm |
Hg | ≤0.05ppm |
As | ≤0.5ppm |
Cu | ≤5ppm |
Pb | ≤0.5ppm |
Pesticide Residue | |
BHC | ≤0.2 ppm |
DDT | ≤0.2ppm |
PCNB | ≤0.1 ppm |
Microbiological Tests | |
Total plate count | ≤2000cfu/g |
Yeast & molds | ≤200cfu/g |
Salmonella | Negative |
E-Coli | Negative |
4. Gotu Kola Extract Manufacturer Process Flow Chart
5. Gotu Kola Extract Benefits
- Gotu Kola Extract for Wound Healing
Gotu kola extract’s wound healing effect contributes to asiaticoside. Topically using asiaticoside increases the proline content and collagen content, as well as promotes the formation of epithelial tissue, then ultimately promotes wound healing. Experimental research results show that asiaticoside has a significant effect on promoting wound healing for both general wounds and delayed wounds. Moreover, study suggests that the number of scar cell layers and fibroblasts decreased after using asiaticoside. Asiaticoside inhibits the excessive infiltration of T lymphocytes and macrophages in the hypertrophic scar tissue of burns and affects its activity to reduce the release of TGF-β1, thereby preventing scar hyperplasia.
- Gotu Kola Extract for Anti-inflammation
Experiments show that gotu kola extract has certain inhibitory effects on Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus acnes, etc. There are also reports that fresh leaves of gotu kola were used to treat furuncle. In addition, gotu kola extract’s properties to soothe and repair irritated dermis are good for sensitive skin prone to redness and acne. Taking advantage of this benefit, gotu kola extract can be used to treat acne or be used in disposable hygiene products.
- Gotu Kola Extract for Anti-aging
Gotu kola extract can stimulate fibroblast proliferation and activate SMAD signaling pathways so as to increase the production of type 1 and type 3 collagen. A test among 20 female participants with skin photo-aging proves the effect of 0.1% madecassoside’s combination with 5% vitamin C on the skin for 6 months. As a result, there is an obvious improvement in elasticity, hydration, skin firmness, as well as collagen content.
6. Plamed Gotu Kola Extract Characteristic
- Plamed offers several specification of Gotu kola extracts, which can meet different customers’ needs.
- Plamed Gotu kola extracts are of water-soluble and alcohol-soluble. They are white or off-white powder with good solubility. The appearance is convenient to be added into cosmetic formula.
7. Gotu Kola Extract Uses and Reference Dosage
Gotu kola extract is really a super active cosmetic raw material for sensitive skin, photoaging skin and skin inflammation, as well as treatment of scar, wound, stretch marks.
Product | Reference Dosage |
Gotu Kola Extract | 0.5-2.0% |
Note:
- Gotu kola extractcan’t be heated with a high temperature.
- Dissolve gotu kola extractin water or alcohol, and then add it to the cosmetic formula before emulsification.
Gotu Kola Extract application examples in major cosmetic brands around the world:
Country | Brand | Product |
Japan | Dr.Ci:Labo | Super White 377 VC |
Melty Wink | Eye Gel | |
POLA | B.A The Lotion | |
Switzerland | La Prairie | La prairie Skin Caviar Liquid Lift |
Korea | AHC | UV Capture Plus Pure Mild Sun Cream |
SU:M37 | Water-full Refreshing Toner | |
RNW | DER. PORE Peeling Toner Pad Mild | |
UAS | ORIGINS | Mega-Mushroom Relief & Resilience Soothing Treatment Lotion |
CLINIQUE | Turnaround Revitalizing Lotion | |
France | Sisley | Ecological Compound |
L’ORÉAL | Revitalift anti-wrinkle and firming day cream
Revitalift Eye Cream |
|
China | Biophyto-genesis | Soothing and Anti-redness Essence |
Simpcare | Camellia Soothing Facial Toner
Camellia Soothing Foaming Wash |
|
UMOUA | Anti-acne Gel | |
Voolga | Centella Asiatica Soothing And Repair Mask | |
Winona | Anti-Acne Cream | |
ABBY’S CHOICE | Refreshing Green Mud Cleansing Mask |
8. Gotu Kola Extract Reference Formula
Anti-aging and skin repair mask
Ingredient | Content (%) | Ingredient | Content (%) |
Gotu Kola Extract | 1.5 | Glycerin | 8.0 |
Butanediol | 5.0 | Betaine | 4.0 |
Panthenol | 1.5 | Glyceryl Polymethacrylate | 1.0 |
Aloe Barbadensis Leaf Extract | 0.5 | Hydrolyzed Algae Extract | 0.8 |
Cordyceps Sinensis Extract | 1.2 | Sodium Hyaluronate | 0.15 |
Glycyrrhiza Glabra Extract | 0.9 | Propylene Glycol | 0.9 |
Hydroxyethyl Urea | 0.9 | Water | Add To 100 |
Preservative | 0.9 | Thickener | 0.8 |
Solubilizer | 0.9 |
9. Gotu Kola Extract Safety
- CAFFCIand CFDA both recognize CENTELLA ASIATICA EXTRACT as cosmetic raw material.
- CTFAhas specified CENTELLA ASIATICA EXTRACT as a raw material for cosmetics.
- CENTELLA ASIATICA EXTRACTis listed in The List of Used Cosmetic Ingredient approved by the Ministry of Health of the People’s Republic of China in 2001.
Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.
As a professional gotu kola extract manufacturer, Plamed have been constantly upgrading the production process. We firmly believe that good gotu kola extract and good gotu kola extract price will help customers make good terminal products and help customers win a lasting and broad market.