Anti blue light compositions for skin care
Product: PMAnti-acne® 9997 for Acne Reduction
Customer from: Malaysia
“I received feedback indicating that when a pimple first appears, applying the acne cream twice a day results in a noticeable reduction in size by the next day. For inflamed pimples, applying the cream once alleviates the pain. Additionally, a colleague tested the acne cream on pimples on his head, and observed a reduction in size by the following day.”
Today, I’d like to share with you one of our customers’ feedback about PMAnti-acne 9997 for acne reduction. He added 1% PMAnti-acne 9997 into the cream, and said his colleagues who used the cream showing a very great anti-acne and anti-inflammation efficacy:
More detail about anti-acne ingredient, please visit PMAnti-acne 9997.
Acne, also known as pimples, is a chronic inflammatory skin disease of follicular sebaceous gland unit. Due to various factors such as staying up late, life pressure, air pollution, etc., there are more and more people with acne skin. And consumers are gradually increasing their attention to acne related skin care products. According to the research, there are almost 73.49% end-users who prefer anti-acne products containing natural plant ingredients.
Effects of PMAnti-acne® 9997 for Acne Reduction
Therefore, Plamed develops a natural ingredient PMAnti-acne® 9997 for anti-acne. It’s a natural compound of magnolia officinalis bark extract, pueraria lobata root extract and glycyrrhizinic acid.
Why PMAnti-acne 9997 has such potent effect? Because it plays an all-around role in treating acne by 3 ways:
- Anti-bacterial: At the same dosage of 2%, the inhibition rate to P. acne of PMAnti-acne® 9997 was more than 99.9%, which was 3 times that of metronidazolefor medicinal purposes.
- Oil-control: At the same dosage of 0.5%, the inhibition rate to 5α-reductase of PMAnti-acne® 9997 was nearly twice that of PCA zinc (99%).
- Anti-inflammation: The dosage of PMAnti-acne® 9997 is one-third dexamethasone, and the anti-inflammatory effect is much stronger.
PMAnti-acne® 9997 for Acne ReductionTest in Vivo
Plamed done the anti-acne test in human skin. Five subjects who met the criteria were recruited to evaluate the anti-acne efficacy of cosmetics by instrument test and visual evaluation. The concentration of PMAnti-acne® 9997 in the formulation is 1%. After cleansing and toning in the morning and evening, apply appropriate amount of this product evenly to the facial skin, gently massage until absorbed.
After using the test product for 8 hours, the volume of the test sample area of the subjects was significantly different from the baseline value. After using the test product for 24 hours, there was a very significant difference in the volume of the test sample area compared with the baseline value. After using the test product for 32 hours, there was a very significant difference in the volume of the test sample area compared with the baseline value.
Note: Significance labeling method: “n.s.” means no statistical difference, P>0.05; “*” indicates significant difference, 0.01<P< 0.05; “**” indicates very significant difference, 0.001 <P <0.01; “***” indicates extremely significant difference, P< 0.001.
After using the test product for 8 hours, the number of acne in the test sample area of the subjects was significantly different from the baseline value. After using the test product for 24 hours, the number of acne in the test sample area of the subjects was significantly different from the baseline value. After using the test product for 32 hours, the number of acne in the test sample area of the subjects was significantly different from the base value.
Note: Significance labeling method: “n.s.” means no statistical difference, P > 0.05; “*” indicates significant difference, 0.01<P<0.05; “**” indicates very significant difference, 0.001 <P<0.01; “***” indicates extremely significant difference, P<0.001.
After using the product containing 1% PMAnti-acne® 9997, there is no any adverse events occurred in the test, which means PMAnti-acne® 9997 is not only effective for acne treatment, but also of high safety to the skin. Here is some effective samples after using PMAnti-acne® 9997 product.
PMAnti-acne® 9997 Solubility in Cosmetics Formulation
We also test PMAnti-acne® 9997’s solubility in different solvents. Measure 10g of 1,3-propanediol, 1,2-pentanediol, 1,2-hexanediol, and glycerol (glycerin), add a certain amount of PMAnti-acne® 9997 sample, and ultrasonically dissolve it at room temperature, observe the dissolution phenomenon, and if it is completely dissolved, then continue to add a certain amount of PMAnti-acne® 9997 sample, and ultrasonically dissolve it at room temperature until insoluble material appears, stop adding. The total weight of the added PMAnti-acne® 9997 sample is recorded and the maximum solubility is calculated.
| Dissolution method | Dissolving temperature | Solvents | Solvents amount/g | Solubility g/10g |
| Ultrasonic dissolving | Room temperature | 1,3-propanediol | 10 | ≤1 |
| Ultrasonic dissolving | Room temperature | 1,2-pentanediol | 10 | ≥6.0 |
| Ultrasonic dissolving | Room temperature | 1,2-hexanediol | 10 | ≥5.5 |
| Ultrasonic dissolving | Room temperature | Glycerol (glycerin) | 10 | Practically insoluble |
In conclusion, PMAnti-acne® 9997 can be soluble in 1,3-propanediol, 1,2-pentanediol, 1,2-hexanediol, but not soluble in glycerol (glycerin).
We have test reports in vivo and in vitro to prove PMAnti-acne® 9997 for Acne Reduction, also have safety testing for it. In addition, we are apply patent for this effective ingredient. Welcome to request samples for your evaluation, maybe it will be an effective natural solution for your anti-acne formulation.
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