1. Capsaicin Overview
Capsaicin, also called trans-8-methyl-N-Vanilyl-6-nonenamide, Capsaicinoids, is an extremely spicy vanilla amide alkaloid. Natural Capsaicin is a mixture of alkaloids, mainly including capsaicin, dihydrocapsaicin, homoea psaiein, homodihydrocapsaicin, nordihydrocapsaicin. Capsaicin has the highest content (0.1-0.4%) in chili seeds; and the content of peel is very low. Plamed Capsaicin is a cosmetic grade raw material of natural plant origin, with a purity of up to 98%. It is light yellow to white crystalline powder. It’s easy to release strong pungent odor at high temperature. Capsaicin is insoluble in water; soluble in ethanol, petroleum ether, acetone, methanol, chloroform and benzene. It is also soluble in alkaline solutions.
As an alkaloid, Capsaicin has many biological activities: 1) Capsaicin has a broad spectrum of antibacterial property. It can help treat various itching and skin diseases such as psoriasis, urticaria, eczema, pruritus, etc. Additionally, it acts as preservative in cosmetics. 2) Capsaicin can enhance the ability of fat metabolism, and accelerate the burning of body fat. It prevents excessive fat accumulation. So it can be used in weight loss products. 3) Certain concentration Capsaicin can improve blood circulation in capillaries. Thereby, it promotes hair growth. Capsaicin can also improve skin metabolism, so as to achieve skin care effect. 4) Capsaicin is a natural febrile agent. It can quickly and efficiently penetrate into skin and cause heat. And it greatly dispels coldness. Capsaicin, as a plant alkaloid from natural source, has great market prospect in the application of cosmetics.
| Product Name | CAS Number | INCI | |
| Capsaicin | 404-86-4 | CAPSAICIN | |
| Molecular Weight | Molecular Formula | Molecular Structure | |
| 305.41g/mol | C18H27NO3 |  |
|
| Product ID | Specification | Minimal Package | Minimal Order Quality |
| PMJY0501 | 98% | 1KG | 1KG |
2. Capsaicin Source
Chili (Latin name: Capsicum annuum L) is a perennial plant of genus Capsicum in Solanaceae family. Its origin is in tropical Latin America such as Mexico. It is planted all over the world. The main producing areas of chili in China are Shaanxi, Henan, Sichuan, Hunan, Yunnan and other provinces. People usually eat its fruit part. Chili has a spicy taste because it contains Capsaicin. Capsicum is rich in nutrients, mainly including capsaicin, vitamins, free amino acids, proteins, carotenoids and soluble sugars. Capsaicin is the main active ingredient for antiseptic and antibacterial in chili. Capsaicin was first isolated and named in 1876. There are major five components: Capsaicin, Dihydrocapsaicin, Nordihydrocapsaicin, Homodihydrocapsaicin, Homoea Psaiein. Capsaicin and dihydrocapsaicin account for more than 90% of total capsaicins. Capsicum extract is widely used in various fields, with potential economic value and broad development prospects
3. Capsaicin VS Nonivamide
| Capsaicin | Nonivamide | |
| Source | Dried fruits of chili | Chemical synthesis |
| CAS No. | 404-86-4 | 2444-46-4 |
| Molecular Formula | C18H27NO3 | C17H27NO3 |
| Molecular Weight | 305.41g/mol | 293.40g/mol |
| Molecular Structure | |
 |
| Component | Capsaicin, dihydrocapsaicin, and other components of capsaicin; they work together. | Only capsaicin |
| Effect | Antibacterial, anti-pruritic, weight loss; promote blood vessel circulation. | Analgesia and antipruritic, antiphlogistic sterilization, treatment of soft tissue injury. |
| Application | Cosmetics | Medicine, military, food, feed, etc |
| Market price | 12000 | 2800 |
4. Capsaicin Manufacturer Specifications
| Product Name | Specification |
| Capsaicin | 98% |
| Items | Specification |
| Capsaicinoids | ≥98% |
| Capsaicin | ≥55% |
| Dihydrocapsaicin | ≥20% |
| Total Content of Other Capsaicin | ≤15% |
| Appearance | Light yellow to white crystal powder |
| Odor | Characteristic |
| Taste | Spicy |
| Physical Characteristics | |
| Solubility | Soluble in acetone, methyl alcohol; Insoluble in water |
| Melting range | 57-66℃ |
| Loss on drying | ≤1% |
| Ash | ≤1% |
| Heavy Metals | |
| Pb | ≤10.0ppm |
| As | ≤2.0ppm |
| Microbiological Tests | |
| Total plate count | ≤1000cfu/g |
| Yeast & mold | ≤100cfu/g |
| Escherichia coli | Negative |
| Salmonella | Negative |
5. Capsaicin Manufacturer Flow Chart
6. Capsaicin Benefits
- Anti-bacterial and analgesic
Capsaicin has an obvious inhibitory effect on Bacillus cereus and Bacillus subtilis; but it has no inhibitory effect on molds. It is a selective antibacterial agent. Capsaicin has therapeutic and conditioning functions for allergic skin. Capsaicin is stable in different pH ranges, and it can exert bacteriostatic effect under neutral conditions. Its antibacterial effect is also stable at high temperature. At the same time, Capsaicin is an antagonist of substance P. It has an analgesic effect on pain caused by chemical substances. But it’s ineffective against mechanical pain. So Capsaicin is a selective pain blocker. Also it has an anti-inflammatory effect.
- Weight loss
Studies have shown that Capsaicin has a significant role in treatment of obesity. Capsaicin can reduce fat absorption in the intestine; and it promotes metabolism rate to improve fat burning in body. Capsaicin entering the human body can accelerate the secretion of neurotransmitters, including acetylcholine and norepinephrine. Adrenaline can effectively help lose weight by sweating and burning fat.
7. Plamed Capsaicin Characteristic
- Plamed possess chili planting base, which can supply the product stably.
- Plamed Capsaicin is derived from natural plant, without synthetic ingredient.
8. Capsaicin Application & Dosage
Capsaicin is mainly used as a cosmetic additive in slimming, antibacterial and anti-allergic cosmetics, as well as in hair products to promote hair growth.
| Application | Recommended Dosage |
| Toner, essence, cream, emulsion, etc. | 0.1-1% |
| Shampoo, conditioner | 0.01-1% |
Capsaicin application cases in major cosmetic brands in the world:
| Country | Brand | Product |
| New Zealand | Ukiwi | Kiwifruit Lifting Body Lotion |
| Brazil | Brazilian Menthol | Pain Relieving Cream |
| France | OULISI | Slimming Cream |
| USA | Castiva | Arthritis Pain Relief |
9. Capsaicin Reference Formula
Anti-wrinkle emulsion
| Ingredient | Content (%) | Ingredient | Content (%) |
| Capsaicin | 0.01 | Magnesium Aluminium Silicate | 1.5 |
| PSS | 12 | Cellulose Gum（CMC7LF） | 1 |
| Collagen | 3 | Preservative | Appropriate |
| Distilled Water | 82.4 | ||
Anti-aging toner
| Ingredient | Content (%) | Ingredient | Content (%) |
| Capsaicin | 0.01 | Azelaic Acid | 20 |
| Tween 20 | 5 | Benzoic Acid | 0.1 |
| Salicylic Acid | 2 | Sodium Dodecyl Phosphate | 20 |
| Vitamin C | 1 | Dodecyl Phosphate Ethanolamine | 1 |
| Olive Oil | 1 | Glyceryl Monostearate | 2 |
| Purified Water | 2 | Hexadecanol | 3 |
Anti-oxidation cream
| Ingredient | Content (%) | Ingredient | Content (%) |
| Capsaicin | 0.01 | Vaseline | 4.5 |
| Tween | 1.25 | Liquid Alcohol | 3.25 |
| Salicylic Acid | 0.09 | Cetyl Alcohol | 1.6 |
| Vitamin A Palmitate | 0.63 | Stearyl Alcohol | 1.6 |
| Vitamin E Acetate | 2 | Glyceryl Monostearate | 3.1 |
| Hydrogen Peroxide (30%) | 4 | Purified Water | Add To 100 |
Skin care cream
| Ingredient | Content(%) | Ingredient | Content(%) |
| Capsaicin | 0.01 | Triethanolamine | 1 |
| Stearic Acid | 1.5 | Heptadecyl Aliphatic Acid | 4 |
| Hexadecanol | 1 | Vitamin B12 | 0.05 |
| Pentadecanol | 0.5 | Vitamin H | 0.05 |
| Vaseline | 4 | Fragrance | 0.4 |
| Paroline | 8 | Purified Water | Add To 100 |
Shampoo:
| Ingredient | Content (%) | Ingredient | Content (%) |
| Capsaicin | 0.03 | Camellia Japonica Seed Oil | 69 |
| Saw Palmetto Berry P.E. | 30 | Ginsenosides | 1 |
10. Capsaicin Safety
- FDA has considered Capsaicin as GRAS.
- Capsaicin has been listed as INCI. It is used as a cosmetic raw material. There are no unsafe reports for its external use.
- Capsaicin is assessed by Cosmetic ingredient review (CIR) Expert Panel as a safe and effective cosmetic ingredient when using without irritation.
- Capsaicin can be added into cosmetics and personal care products sold in European, according to general provisions of the Cosmetics Regulation of the European Union
11. Packing and Storage
Package: Packed in 25kg paper drums with two plastic bags inside.
Storage: Stored in a cool dry place and away from direct sunlight and oxidizing agents.
Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.
As a professional Capsaicin manufacturer, Plamed have been constantly upgrading the production process. We firmly believe that good Capsaicin and good Capsaicin price will help customers make good terminal products and help customers win a lasting and broad market.
