1. Aescin Overview
Aescin, also known as Escin, Horse Chestnut Extract, is a pentacyclic triterpenoid saponin. It is a mixture of several structurally similar isomers; and the components are not easily separated. Aescin is derived from dried seeds of horse chestnut. It is crystalline powder. Aescin is hardly soluble in water, slightly soluble in cold alcohol; and it is soluble in methanol and ethanol. Plamed develops two specifications Aescin: 98% and 20%. Both of them are 100% natural cosmetic raw materials.
Aescin, as a saponin compound, is a surfactant, as well as of a strong foaming ability. It can be used as a detergent and foaming agent. Additionally, Aescin exerts anti-inflammatory effect. It can alleviate skin allergies; and it can prevent and treat skin erythema, inflammation and allergies. Moreover, Aescin can promote blood circulation. It promotes wound healing, and possesses anti-edema property. Thus it can be used in cosmetics for removing eye dark circles, anti-redness, anti-wrinkle, and repairing skin.
Product Name | CAS Number | INCI | |
Aescin | 6805-41-0 | ESCIN | |
Molecular Weight | Molecular Formula | Molecular Structure | |
1131.26 g/mol | C55H86O24 | ||
Product ID | Specification | Minimal Package | Minimal Order Quality |
PMM0301 | 20% | 1KG | 1KG |
98% | 100g | 100g |
2. Aescin Source
Horse chestnut (Latin name: Aesculus chinensis Bunge), also known as conker tree, is a deciduous plant of Sapindaceae family. Its seed is close to spherical; color is chestnut brown. The seed can be eaten after cooking with alkaline water. Also it can be used for medicinal purpose. The artificial cultivation area of horse chestnut is mainly distributed in the Yellow River Basin and the eastern provinces of China. The Qinling Mountains has wild distribution. It generally grows in mountains below 700 meters above sea level. The fruit of horse chestnut contains a large number of saponin compounds, mainly Aescin. And its seed is rich in fatty oil, crude protein, fiber, starch, etc; it is a traditional Chinese medicine. The seed is mainly used for cosmetics.
3. Aescin Manufacturer Specifications
Product Name | Specification |
Aescin | 20%, 98% |
Aescin 98% Specifications
Items | Specification |
Assay(Titration) | ≥98.0% |
Appearance | Almost white or light-yellow powder |
Extract solvent | Water & ethanol |
Physical Characteristics | |
Particle size | 98% through 80 mesh |
Moisture | ≤5.00% |
Ash content | ≤5.00% |
Rotation | -24.0~-30.0 |
pH value | 3~5 |
Solvent residue | European standard |
Heavy Metals | |
Heavy metals | ≤10ppm |
Arsenic | ≤2ppm |
Microbiological Tests | |
Total Plate count | ≤1000cfu/g |
Yeast & mold | ≤100cfu/g |
Escherichia coli | Negative |
Salmonella | Negative |
Aescin 20% Specifications
Items | Specification |
Assay | ≥20.0% |
Appearance | Fine powder |
Odor | Characteristic |
Taste | Characteristic |
Extract solvent | Water & ethanol |
Drying method | Spraying drying |
Physical Characteristics | |
Particle size | 98% through 80 mesh |
Moisture | ≤5.00% |
Ash content | ≤5.00% |
Solvent residue | European standard |
Heavy Metals | |
Heavy metals | ≤10ppm |
Arsenic | ≤2ppm |
Plumbum | ≤2ppm |
Cadmium | <0.5ppm |
Mercury | <0.5ppm |
Microbiological Tests | |
Total Plate count | ≤1000cfu/g |
Yeast & mold | ≤100cfu/g |
Escherichia coli | Negative |
Salmonella | Negative |
Aescin 98% chromatogram
4. Aescin Manufacturer Flow Chart
5. Aescin Benefits
- Anti-redness
Aescin can fill small gaps in tiny veins and finely visible gaps. Thereby, it effectively reduces vascular permeability, and improves integrity of vessel wall. Aescin is helpful to repair capillaries. Therefore, Aescin can be used to repair facial redness.
- Anti-Inflammation
Aescin has an inhibitory effect on activity of phospholipase A2. Phospholipase A2 is not only involved in cell transmembrane information transmission, but also a key enzyme in production of inflammation and allergic mediators. Therefore, Aescin shows a certain anti-inflammatory property. It can relieve allergic skin, and prevent moisture accumulation in tissues. Also it quickly eliminates the heavy feeling and pressure caused by local edema. Aescin can remove eye edema and dark circles.
6. Study on the Pharmacology of Aescin and Cosmetics
Test item | Concentration | Result |
Promotion to ATP production by cell culture | 0.5μg/mL | Promotion rate:143.6 ( blank 100) |
Inhibition to phospholipase A2 activity | 0.5μg/mL | Inhibition rate:36.3% |
Inhibition to swelling of rat toes | 0.075% | Inhibition rate:58.6% |
Inhibition to granulation swelling of cotton ball in rats | 0.5mg/kg | Inhibition rate:20.1% |
Inhibition to IL-1βproduction induced by LPS | 0.1mg/mL | Inhibition rate:20.1% |
Inhibition to activity of hyaluronidase | IC50:(149.9±2.6)μmol/L |
7. Plamed Aescin Characteristic
- Complete specifications, which are able to provide customers with different choices.
- Plamed has a self-controlled planting base of horse chestnut. Aescin’s supply is stable.
8. Aescin Application & Dosage
Aescin is mainly used in cosmetics.
- Because of its foaming ability, Aescin can be used in bath dew, shampoo, cleanser foam.
- Due to its anti inflammatory property, Aescin can be added into eye cream, lotion and essence, cream, facial mask.
- Aescin can repair capillary activity, so it can be applied in anti-redness cosmetics.
Specification | Recommended Dosage |
Aescin 20% | 5-10% |
Aescin 98% | 0.25-1% |
Application | Recommended Dosage |
Removing both cellulite and much water retention | 0.8% |
Anti-redness | 0.4% |
Aescin application cases in major cosmetic brands in the world:
Country | Brand | Product |
France | Clarins | Extra-Firming Eye Complete Rejuvenating Cream
Shaping Facial Lift Total contouring Serum Lift-Affine Visage Body Lift Cellulite Control |
Lancome | Advanced Genifique Yeux Light-Pearl
Hydra Zen Yeux Eye Contour Gel Cream |
|
Caudalie | Anti-Wrinkle Eye & Lip Cream
1st Wrinkle Eye Cream by Caudalie |
|
Chanel | Hydra Beauty Micro Gel Yeux
Le-lift Fermete-Anti-Rides Creme Yeux |
|
Helena | Rubinstein Power Cell Eye Care
Rubinstein for Ce C Booster Fluid Rubinstein Re-Plasty Laserist Spot Concentrate |
|
Vichy | Lift Activ Eyes Supreme | |
SVR | Topialyse Creme Emolliente Soothing Cream | |
FILORGA | Sleep-Recover Fatigue Correcting Night Balm | |
China | Chcedo | Pure Nutrient Lotion/Clear Glacier Water |
DR.WU | Intensive Renewal Toner with Mandelic Acid
Daily Renewal Lotion with Mandelic Acid |
|
AFU | Lavender Gentle Clarifying Toner | |
Winona | Anti-Redness Rich Moisturizing Cream
Whitening and Moisturizing Emulsion Extra Moisturizing BB Cream Arbutin Whitening Mask |
|
USA | Marykay | Calming Influence Mask
Calming Influence Serum Calming Influence Freshener |
KIEHL‘S | Powerful-Strength Line-Reducing Eye-Brightening Concentrate | |
Korea | Su:m 37º | Secret Programming Eye Cream |
9. Aescin Reference Formula
Emulsion
Ingredient | Content (%) | Ingredient | Content (%) |
Aescin | 0.5 | Hydrogenated Lanolin | 2.0 |
Stearic acid | 2.5 | Glycerol monostearate | 2.0 |
Octyl laurate | 5.0 | Polyoxyethylene 20 cetyl ether | 3.0 |
Octadecanol | 6.0 | Fragrance | Appropriate |
Squalane | 6.0 | Purified water | Add to 100 |
Anti-perspiration tincture
Ingredient | Content (%) | Ingredient | Content (%) |
Aescin | 0.2 | Esculinsesquihydrate | 0.2 |
Glycyrrhizic acid | 0.2 | β-sitosterol | 0.2 |
Sage oil | 1.0 | 95% ethanol | Add to 100 |
Essence
Ingredient | Content (%) | Ingredient | Content (%) |
Aescin | 0.003 | Ascophyllum nodosum extract | 0.003 |
Octylene glycol | 0.41 | Blackberry leaf extract | 0.04 |
Fragrance | 0.25 | Argania spinosa kernel oil | 0.75 |
Xanthan gum | 0.25 | Acrylate/c10-30 alkyl acrylate crosslinked polymer | 0.30 |
Cetostearyl alcohol | 0.39 | 1,3-propanediyl ester | 1 |
Maltodextrin | 0.46 | Dipropylene glycol | 0.48 |
Cetanol | 0.5 | Phenoxyethanol | 0.52 |
Glycollic acid | 0.56 | Allyl dimethyl-taurine /VP copolymer | 1 |
Jojoba lipids | 0.75 | Triethanolamine | 0.8 |
Water | 65 | Caprylic triglyceride | 1 |
Pentanediol | 1 | Ethoxydiglycol | 1 |
Menthyl lactate | 0.25 | Coleus barbatus root extract | 1 |
Caffeine | 1 | Cyclopentasiloxane | 3 |
Sorbitol | 3.5 | Glycerin | 5 |
Modified alcohol | 8.3 | Polydimethylsiloxane | 1.6 |
Excipient | Appropriate |
Shower gel
Ingredient | Content (%) | Ingredient | Content (%) |
Aescin | 0.5~1 | Camellia saponins | 3~7 |
Hederin | 4~6 | Sapindoside | 0.5~1.5 |
Camellia oil | 3~5 | Glycyrrhizic acid | 0.1~0.5 |
Hovenosides | 0.5~1 | Lycyoside | 0.1~0.5 |
Baicalin extract | 2~5 | Garlic extract | 1~3 |
Citric acid | 0.1~0.5 | Tremella fuciformis extract | 3~5 |
Starch | 1~3 | Momordica charantia extract | 1~3 |
Sodium citrate | 0.1~0.5 | Sodium chloride | 0.1~0.5 |
Deionized water | 40~50 |
10. Aescin Safety
- Aescin has been specified as cosmetic raw material by Cosmetic, Toiletry & Fragrance Association (CTFA).
- Aescin is listed on The International Catalogue of Chinese Cosmetic Raw Materials Standards in 2010 published by CAFFCI and On the Announcement of Name List of Cosmetics Raw Material issued by CFDA in 2014.
11. Packing and Storage
Package: Packed in 25kg paper drums with two plastic bags inside.
Storage: Stored in a cool dry place and away from direct sunlight and oxidizing agents.
Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.
As a professional Escin manufacturer, Plamed have been constantly upgrading the production process. We firmly believe that good Escin and good Escin price will help customers make good terminal products and help customers win a lasting and broad market.
Other Skin-whitening Product List
NO. | Product Name | Product ID | Specification | Product Image |
---|---|---|---|---|
01 | Arbutin | PMB0101 PMB0102 | Alpha 99.5% Beta 99.0% | |
02 | PCR Glabridin | PMB0705PCR | 10% | |
03 | Kojic Acid Dipalmitate | PMB0801 | 99% | |
04 | D-alpha Tocopherol Acetate | PMB0901 PMB0902 | 700IU 1300IU | |
05 | Bakuchiol | PMKZ1501 | 98% | |
06 | Grape seed extract | PMB1401 | 95%OPC | |
07 | Ellagic Acid | PMB0401 | 98% | |
08 | Glabridin | PMB0705,PMB0702 PMB0703,PMB0704 | 10%,40% 90%,98% | |
09 | Glutathione | PMB1601 | 98% | |
10 | Ascorbic Acid 2-Glucoside | PMB1801 | 98% | |
11 | Phloretin | PMB0301 | 98% | |
12 | Lycopene | PMB1101 | 80% | |
13 | Resveratrol | PMB0501 | 98% | |
14 | Green Tea Extract | PMB1501, PMB1502, PMB1503 | 95% EGCG, 70% oil-soluble polyphenols, 98% water-soluble polyphenols | |
15 | Luteolin | PMB1301 | 98% | |
16 | Chrysin | PMB1001 | 99% | |
17 | Puerarin | PMB1201 | 98% | |
18 | Escin | PMM0301 | 20%, 98% | |
19 | Tetrahydrocurcumin | PMB0201 | 98% | |
20 | Nicotinamide | PMB1501 | 99% | |
21 | Curcumin | PMB2501 | 10% | |
22 | Rhodiola-crenulata-extract | PMB2401 | 2% Salidroside |