1. Puerarin Overview
Puerarin is a kind of isoflavone monomer in Pueraria flavone. It accounts for about 50% of the total amount of Pueraria isoflavones. Puerarin is found in the dried root of pueraria lobata, and its content is about 2.3%. Plamed Puerarin is natural cosmetic grade raw material with 98% specification. It is white crystalline powder; It’s slightly soluble in water, soluble in methanol, hot ethanol and ethyl acetate. And Puerarin will not cause glucoside hydrolysis in alkaline solution.
Puerarin has been praised by international cosmetics industry as a kind of skin decoloration component derived from green plant. It has been used in whitening cosmetics in many countries, such as Japan, Europe countries and America, where cosmetics technology is leading. This is because Puerarin has strong activity to inhibiting tyrosinase. It achieves whitening effect by inhibiting tyrosine dynamic enzyme. Moreover, Puerarin has absorption ability to UVA~UVB. It can prevent various color spots caused by sunlight exposure. In addition, Puerarin is easy to be absorbed by skin. It can not only synergize with other nutrients, but also stimulate hair growth. Also it can regulate skin, and increase moisturizing capacity. At the same time, Puerarin can dilate blood vessel, stimulate blood circulation, and improve microcirculation. Puerarin strengthens accumulation of breast fat, so as to make breast become plump again. Therefore, Puerarin can be used in breast enhancement products.
Product Name | CAS Number | INCI | |
Puerarin | 3681-99-0 | PUERARIN | |
Molecular Weight | Molecular Formula | Molecular Structure | |
416.38g/mol | C21H20O9 | ||
Product ID | Specification | Minimal Package | Minimal Order Quality |
PMB1201 | 98% | 1KG | 1KG |
2. Puerarin Source
Kudzu is the dry root of Leguminosae. It is mainly divided into pueraria lobata and pueraria thomsonii. Both contain pueraria flavone. The main components of pueraria flavone include puerarin, hydroxy puerarin, methoxypuerarin, daidzin, as well as triterpenes and coumarins.
Pueraria lobata | Pueraria thomsonii | |
Introduction in Chinese Pharmacopoeia (2015) | Dried root of Pueraria lobata | Dried root of Pueraria thomsonii |
Distribution | Mainly in Henan, Shaanxi, Anhui, Zhejiang. Shaanxi is the largest producer of pueraria in the north | Mainly in Guangxi, Guangdong. Also in Jiangxi, Hunan, Sichuan, Yunnan. |
Content of Puerarin | 2.3% or so | Only 0.3% |
Effect | Widens the coronary arteries, enhances the metabolism of myocardium, resists arrhythmic, Improves microcirculation and brain circulation, and lowers blood pressure, lowers blood sugar, lowers blood lipid | Promotes the secretion of saliva and quenches thirsty, antidiarrheal, relieves alcoholism |
Application | Contains many medicinal ingredients. It can be used in medicine, health care products and cosmetics | Using starch and isoflavones as raw materials isolating from pueraria thomsonii can make variety of products including pueraria powder, pueraria tea and pueraria beverage. It is a good health care food |
3. Puerarin Manufacturer Specifications
Product Name | Specification |
Puerarin | 98% |
Items | Specification |
Assay | Puerarin≥98% |
Color | White crystalline powder, no odor, no impurities |
Physical Characteristics | |
Particle Size | 98% through 80 mesh |
Moisture | ≤1.00% |
Ash Content | ≤1.00% |
Heavy Metals | |
Arsenic | ≤1.0ppm |
Plumbum | ≤1.0 ppm |
Mercury | ≤0.1 ppm |
Cadmium | ≤0.1 ppm |
Microbiological Tests | |
Total Plate count | ≤1000cfu/g |
Yeast & mold | ≤100cfu/g |
Escherichia coli | Negative |
Salmonella | Negative |
4. Puerarin Manufacturer Flow Chart
5. Puerarin Benefits
- Whitening
Puerarin can effectively inhibit catalytic activity of tyrosinase. It interrupts oxidation process of melanin, and inhibits occurrence and formation of melanin. Moreover, Puerarin has certain ability of ultraviolet absorption, so it can prevent pigment deposition including chloasma and sunburn. Thereby, Puerarin exerts its whitening and freckle effect.
- Anti-oxidation
Structurally, Puerarin contains two phenolic hydroxyl groups. It is a isoflavone compound. This is the structural basis on which Puerarin has activity of scavenging oxygen free radicals. Puerarin can significantly inhibit RBC hemolysis caused by oxidative damage; also it inhibits peroxidation caused by reactive oxygen species. Additionally, Puerarin improves SOD activity in vivo; and it regulates the balance between oxygen free radical and free radical scavenger in the body. Experimental study has also shown that Puerarin can clear superoxide anion and ·OH. It exhibits certain antioxidant and anti-aging effect.
6. Study on the Pharmacology of Puerarin and Cosmetics
Test item | Concentration | Result |
Elimination to superoxide free radicals | 1.0mmol/L | Elimination rate:93.9% |
Elimination to hydroxyl radicals | 0.075 mmol/L | Elimination rate:85.0% |
Inhibition to lipid peroxidation | 2.0 mmol/L | Inhibition rate:75% |
Inhibition to tyrosinase activity | 0.75% | Inhibition rate:51.8% |
Promotion to skin cuticle moisture content by electrical conductance measurement | 3% | Promotion rate:114.0(blank 100) |
Inhibition to IL-6 production | 8mg/kg | Inhibition rate:39.4% |
7. Plamed Puerarin Characteristic
- Plamed Puerarin is isolated from pollution-free wild pueraria lobata. And it is of low pesticide residues and low heavy metals.
8. Puerarin Application & Dosage
Puerarin, as a natural skin whitening ingredient, is widely used in whitening cosmetics such as toner, essence, emulsion, facial mask, sunscreen and skin care gel. It can also be added in shampoo to promote hair growth.
Application Product | Recommended Dosage |
Whitening cosmetics | 0.1-0.2% |
Breast enhancement paste or cream | 0.1-1.0% |
Shampoo, conditioner | 2% |
Puerarin application cases in major cosmetic brands in the world:
Country | Brand | Product |
Japan | Quality First | All in One Sheet Mask Pink)
All in One Sheet Mask |
Dr.Ci:Labo | Aqua-Collagen-Gel Super Sensitive
Aqua-Collagen-Gel Super Moisture Aqua-Collagen-Gel Enrich-Lift EX Washing Foam Super Sensitive UV and White Protection Milk SPF 50/PA+++ Washing Foam Super Sensitive |
|
POLA | B.A The Lotion | |
DHC | Mineral Mask
Acerola Lotion Alpha-Arbutin White Cream |
|
AKARAN | Essential Water Gel | |
Rohto | Atorrege ad+ 2 Lotion
Atorrege AD+ 2 Emulsion |
|
Albion | Ex-Vie Cream S | |
USA | AVON | Anew Fairness Intensive Serum
Anew Fairness Cream |
Estee Lauder | CyberWhite HD Advanced Spot Correcting Essence | |
Korea | AHC | Sunscreen SPF50+ PA+++ |
ReEn Yungo | The First Cleansing Treatment | |
Acwell | Aqua Clinity Cream | |
UK | Charmzone | Ginkgo Cleansing Cream |
China | Chando | Cellcrystal Brightening Cleanser
Luna-Whitening Hydratation Lotion Luna-Whitening Hydratation Eye Cream |
DR.WU | Gentle Cleansing Mousse With Amino Acids
Perfect Cover Blemish Balm Cream |
|
FOR BELOVED ONE | Active Anti-Wrinkles Bio-Cellulose Mask |
9. Puerarin Reference Formula
Skin-lightening cream
Ingredient | Content(%) | Ingredient | Content(%) |
Puerarin | 0.2 | Monoglyceride | 5.0 |
EDTA Na | 0.1 | Ethylene glycol monostearate polyoxyethylene ether | 2.0 |
Kojic acid | 1.5 | Glycerin tricaprylate | 8.0 |
Squalane | 8.0 | Sodium citrate | 1.0 |
Stearyl alcohol | 5.5 | Fragrance, preservative | Appropriate |
Dimethyl polysiloxane | 0.2 | Purified water | Add to 100 |
Propylene glycol | 5.0 |
Skin-whitening paste:
Ingredient | Content(%) | Ingredient | Content(%) | |
A phase | Puerarin | 5.00 | 1,3 Butanediol | 5.00 |
Hyaluronic acid | 0.20 | EDTA | 0.05 | |
Deionized water | 64.15 | |||
B phase | Stearyl alcohol | 6.00 | Squalane | 3.00 |
Caprylic triglycerides | 3.00 | Isopropyl myristate | 3.00 | |
Brij 72 | 2.00 | Brij 721 | 2.00 | |
Monoglyceride | 2.00 | Vitamin E acetate | 1.00 | |
Dimethicone (100cs) | 3.00 | |||
C phase | Fragrance | 0.20 | Germall plus | 0.20 |
Preparation method:
Heat A phase ingredients to 90-95℃; heat B phase ingredients to 85℃. Then mingle the two phases ingredients quickly. Stir and then emulsify; homogenize for 3min. And slowly stir until 45℃ then add C phase ingredients; stir until cooling down.
10. Puerarin Safety
- Puerarin has been specified as cosmetic raw material by Cosmetic, Toiletry & Fragrance Association (CTFA).
- Puerarin is listed on The International Catalogue of Chinese Cosmetic Raw Materials Standards in 2010 published by CAFFCI.
11. Packing and Storage
Package: Packed in 25kg paper drums with two plastic bags inside.
Storage: Stored in a cool dry place and away from direct sunlight and oxidizing agents.
Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.
As a professional Puerarin manufacturer, Plamed have been constantly upgrading the production process. We firmly believe that good Puerarin and good Puerarin price will help customers make good terminal products and help customers win a lasting and broad market.
Other Skin-whitening Product List
NO. | Product Name | Product ID | Specification | Product Image |
---|---|---|---|---|
01 | Arbutin | PMB0101 PMB0102 | Alpha 99.5% Beta 99.0% | |
02 | PCR Glabridin | PMB0705PCR | 10% | |
03 | Kojic Acid Dipalmitate | PMB0801 | 99% | |
04 | D-alpha Tocopherol Acetate | PMB0901 PMB0902 | 700IU 1300IU | |
05 | Bakuchiol | PMKZ1501 | 98% | |
06 | Grape seed extract | PMB1401 | 95%OPC | |
07 | Ellagic Acid | PMB0401 | 98% | |
08 | Glabridin | PMB0705,PMB0702 PMB0703,PMB0704 | 10%,40% 90%,98% | |
09 | Glutathione | PMB1601 | 98% | |
10 | Ascorbic Acid 2-Glucoside | PMB1801 | 98% | |
11 | Phloretin | PMB0301 | 98% | |
12 | Lycopene | PMB1101 | 80% | |
13 | Resveratrol | PMB0501 | 98% | |
14 | Green Tea Extract | PMB1501, PMB1502, PMB1503 | 95% EGCG, 70% oil-soluble polyphenols, 98% water-soluble polyphenols | |
15 | Luteolin | PMB1301 | 98% | |
16 | Chrysin | PMB1001 | 99% | |
17 | Puerarin | PMB1201 | 98% | |
18 | Escin | PMM0301 | 20%, 98% | |
19 | Tetrahydrocurcumin | PMB0201 | 98% | |
20 | Nicotinamide | PMB1501 | 99% | |
21 | Curcumin | PMB2501 | 10% | |
22 | Rhodiola-crenulata-extract | PMB2401 | 2% Salidroside |