1. Stephania Tetranda Extract Overview
Stephania Tetranda Extract derives from dried roots of stephania tetrandra. The main chemical component is tetrandrine; it is a kind of bisbenzylisoquinoline alkaloid. Tetrandrine has a broad-spectrum anti-inflammatory effect. Also, it can inhibit all aspects of the inflammatory reaction. It can be used as an anti-inflammatory agent for cosmetics. Animal experiments have shown that stephania tetranda extract has good astringent effect on pores. So it can be used for firming cosmetics. Many cosmetic brands have added stephania tetranda extract to mask to exert its anti-inflammatory effect.
| Product Name | CAS Number | INCI | |
| Stephania Tetranda Extract | \ | STEPHANIA TETRANDA ROOT EXTRACT | |
| Product ID | Specification | Minimal Package | Minimal Order Quality |
| PMM1301 | 0.5% Tetrandrine | 1KG | 1KG |
2.Stephania Tetranda Extract Source
Stephania tetrandra is a herbaceous perennial vine of the Menispermaceae family. It is usually born on hillsides, grasses and shrubs. It is native to China and Twain. Stephania tetrandra contains a variety of alkaloids, flavonoids, polyphenols, organic acids and volatile oils, among which mainly isoquinoline alkaloids. The alkaloids are tetrandrine, demethylated tetrandrine, anti-ninoline, and berbamine. Its root is used in traditional Chinese medicine. It is beneficial to swelling and pain relief.
3. Stephania Tetranda Extract Manufacturer Specifications
| Items | Specification |
| Tetrandrine | ≥0.5% |
| Extract part | Root |
| Organoleptic Tests | |
| Appearance | Light yellow powder |
| Odor | Characteristic |
| Taste | Characteristic |
| Physical Characteristics | |
| Particle size | 98% through 80 mesh |
| Moisture | ≤7.0% |
| Ash content | ≤10.0% |
| Heavy Metals | |
| Pb | ≤10(mg/kg) |
| As | ≤2(mg/kg) |
| Hg | ≤1(mg/kg) |
| Cd | ≤5(mg/kg) |
| Microbiological Tests | |
| Total of bacteria | ≤100cfu/g |
| Yeast & mold | ≤20cfu/g |
| Thermotolerant coliforms | Negative |
| P.Aeruginosa | Negative |
| Staphylococcus aureus | Negative |
4. Stephania Tetranda Extract Benefits
- Anti-infalmmation
The alkaloids in Stephania Tetranda Extract has a certain anti-inflammatory effect. It can repair dry skin and aging problem in winter. At the same time, it increases skin comfort and scavenges free radicals to improve skin function.
- Anti-allergic
Stephania Tetranda Extract can prevent release of allergic media. It has a reliable confrontation and therapeutic effect on allergic reactions. It can alleviate skin redness caused by allergies.
5. Plamed Stephania Tetranda Extract Characteristic
- Plamed develops 5% Tetrandrine, a highly active ingredient.
- Plamed develops DMR double membrane filtration technology. The technology makes water solution transparent and clear after dissolution, and no precipitation.
- Plamed adopts WSK decolorization technology that makes product’s color lighter and finer.
Figure: water solution of Stephania Tetranda Extract
6. Stephania Tetranda Extract Application & Reference Dosage
| Application Products | Reference Dosage |
| Facial cleasner, toner, essence, emulsion, cream, mask, etc. | 0.1-2% |
Stephania Tetranda Extract application cases in major cosmetic brands in the world:
| Country | Brand | Product |
| China | UNIFON | Deep clean mineral mud mask
Red pomegranate mineral toner |
| Proya | Purple chlorella soothing repair conditioning mask | |
| Herborist | Infused with ferment filtrate | |
| Mageline | Deep hydrating mask | |
| Maxam | Bamboo intensive moisturizing toner | |
| Inoherb | Quadruple hydrating silk mask
Wild fruit soothing hydrating mask |
7. Stephania Tetranda Extract Reference Formula
Essence
| Ingredient | Content (%) | Ingredient | Content (%) |
| Stephania tetranda extract | 0.2 | Deionized water | 62.0 |
| Butanediol | 30.0 | Hydrolyzed collagen | 5.0 |
| Nicotinamide | 2.0 | Panthenol | 2.0 |
| Sodium hyaluronate | 0.3 | Acetyl hexapeptide -3 | 0.2 |
| Rose extract | 0.15 | rhEGF | 0.15 |
| EDTA | 0.1 |
Massage oil
| Ingredient | Content (%) | Ingredient | Content (%) |
| Stephania tetranda extract | 0.4 | Cyclomethicone | 30.0 |
| Dimethiconol | 10.0 | PEG-50 hydrogenated castor oil | 1.5 |
| Polyethylene glycol-8 | 1.5 | PEG-7 oleate | 3.0 |
| Bisabolol | 0.2 | Allantoin | 0.2 |
| Propylene glycol | 3.0 | Glycerin | 2.0 |
| Xanthan gum | 0.05 | Carbomer | 0.1 |
| Triethanolamine | 0.1 | EDTA | 0.05 |
| Blumea oil | 0.3 | Santal oil | 0.3 |
| Methylparaben | 0.1 | Deionized water | Add to 100 |
8. Stephania Tetranda Extract Safety
- Cosmetic, Toiletry &Fragrance Association (CTFA) has specified Stephania Tetranda Extract as a cosmetics ingredient.
- The safety of Stephania Tetranda Extract is tested in Safety Standards for Cosmetics (2015 edition); and it has no known insecurity for external use.
- Stephania Tetranda Extract is a cosmetic ingredient approved by CFDA (China Food and Drug Administration).
9. Packing and Storage
Package: Packed in 1kg fresco bag with two plastic bags inside.
Storage: Stored in a cool dry place and away from direct sunlight and oxidizing agents.
Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.
As a professional Stephania Tetranda Root Extract, Plamed have been constantly upgrading the production process. We firmly believe that good Stephania Tetranda Root Extract and good Stephania Tetranda Root Extract price will help customers make good terminal products and help customers win a lasting and broad market.
