1. Cosmetics Grade Resveratrol Overview
Resveratrol is a natural plant polyphenol. It is widely found in nature, such as hellebore, polygonum cuspidatum, grape, peanut, pineapple and other plants or fruits. Plamed Resveratrol is extracted from root of polygonum cuspidatum, belonging to natural cosmetics raw material. Resveratrol has strong antioxidant property. It can scavenge free radicals in the body, and promote skin cells’ metabolism. Also it regulates internal and external secretion. It can inhibit melanocytes formation; and its whitening effect is better than arbutin and ethyl ascorbic acid. Resveratrol also has UV absorbency with maximum UV absorption at 366nm. In addition, Resveratrol can inhibit the production of inflammatory related substance TxB2 (a metabolite of arachidonic acid). So it has anti-inflammatory and anti-allergic effect. Resveratrol can promote collagen secretion and SOD activity. Thereby it can improve the ability of skin immune cells, and maintain skin elasticity and thickness. Therefore, Resveratrol can be used as anti-oxidant, whitening agent, sunscreen, anti-inflammatory agent and anti-aging agent in cosmetics. It is of great application value in cosmetic market.
Product Name | CAS Number | INCI Name | |
Resveratrol | 501-36-0 | RESVERATROL | |
Molecular Formula | Molecular Weight | Molecular Structure | |
C14H12O3 | 228.24g/mol | ||
Product ID | Specificcation | Minimal Package | Minimal Order Quantity |
PMB0501 | 98% | 1KG | 1KG |
PMB0502 | 10% water soluble Resveratrol |
2. Cosmetics Grade Resveratrol Botanical Source
Polygonum cuspidatum (Latin name: Reynoutria japonica Houtt.), also known as Japanese knotweed, is a perennial herbaceous plant. It is also a Chinese medicine plant. Its roots are thick and strong, which can be used as medicine. Polygonum cuspidatum is native to east Asia. And now it is widely distributed throughout China, mainly in northwest, north and south China. The dried root of polygonum cuspidatum is a traditional Chinese medicine. It contains a variety of pharmacological active ingredients, including emodin, resveratrol, etc. Therefore, polygonum cuspidatum extract is widely used in medicine industry.
3. Cosmetics Grade Resveratrol Manufacturer Specifications
Product Name | Specification | Color |
Resveratrol | 98%、10% water soluble | White |
10% Water Soluble Resveratrol Specification
Items | Specification |
Assay | ≥10.00% |
Color | White fine powder |
Odor | Characteristic |
Taste | Characteristic |
Extract Solvent | Ethyl acetate/ethanol & water |
Physical Characteristics | |
Particle Size | 98% through 80 mesh |
Moisture | ≤5.0% |
Ash content | ≤5.0% |
Heavy Metals | |
Heavy metals | ≤10ppm |
Arsenic | ≤2ppm |
Plumbum | ≤3ppm |
Mercury | ≤0.1ppm |
Cadmium | ≤1ppm |
Microbiological Tests | |
Total Plate count | ≤1000cfu/g |
Yeast & mold | ≤100cfu/g |
Escherichia coli | Negative |
Staphylococcus | Negative |
Salmonella | Negative |
98% Resveratrol Specification
Items | Specification |
Assay | ≥98.00% |
Color | White fine powder |
Odor | Characteristic |
Taste | Characteristic |
Extract Solvent | Water & ethanol |
Physical Characteristics | |
Particle Size | 98% through 80 mesh |
Moisture | ≤1.0% |
Ash content | ≤0.5% |
Bulk density | 35.0~50.0g/100ml |
Ethyl acetate | ≤10ppm |
Heavy Metals | |
Heavy metals | ≤10ppm |
Arsenic | ≤2ppm |
Plumbum | ≤3ppm |
Mercury | ≤0.1ppm |
Cadmium | ≤1ppm |
Microbiological Tests | |
Total Plate count | ≤1000cfu/g |
Yeast & mold | ≤100cfu/g |
Escherichia coli | Negative |
Staphylococcus | Negative |
Salmonella | Negative |
4. Cosmetics Grade Resveratrol Manufacturer Flow Chart
5. Cosmetics Grade Resveratrol Benefits
- Anti-oxidation
Resveratrol is a natural antioxidant present in plants. Its antioxidant mechanism is mainly to eliminate or inhibit free radicals production. Studies have confirmed that antioxidant effect of Resveratrol is stronger than that of vitamin C and vitamin E. It has strong function of scavenging free radicals and resisting lipid per-oxidation. Furthermore, it can regulate the activity of antioxidant related enzymes.
- Anti-aging
Study on aging of mice by Resveratrol shows that Resveratrol can scavenge free radicals; it can reduce H202 content in skin tissue, and increase the activity of ATP enzyme. The study proves that Resveratrol can resist skin aging caused by lipid peroxidation that is led by free radicals and their metabolites. Thus Resveratrol can improve body immunity, and delay tissue damage. It has certain anti-aging effect.
- Whitening and sun block
Resveratrol can inhibit cell proliferation. It can significantly inhibit tyrosinase activity, and reduce melanin content. Thus Resveratrol plays a role of whitening skin. In addition, Resveratrol has strong UV absorbency. It has maximum UV absorption at 366nm. It can reduce radiation damage to skin caused by ultraviolet light.
- Anti-inflammation and anti-microbial
Resveratrol has inhibitory effect on escherichia coli, pseudomonas aeruginosa and staphylococcus aureus, as well as skin fungi. Experimental result shows that Resveratrol has certain anti-HBV effect in vitro. Its mechanism of action is to inhibit DNA replication of HBV, and to induce apoptosis of cells infected with HBV, so as to exert its antiviral activity.
6. Pharmacological studies of Resveratrol and Cosmetics
Test Item | Concentration | Result |
Elimination of free radical DPPH | EC50: (39.5±2.8) μg/mL | |
Inhibition of b-16 melanocytes | 0.02% | Inhibition rate: 53.17% |
Inhibition of tyrosinase activity | IC50: 2.0μg/mL | |
Promotion of collagen production by cell culture | 1.25μmol/L | Promotion rate: 121(blank 100) |
Promotion of fibroblasts proliferation by cell culture | 5μmol/L | Promotion rate: 141(blank 100) |
Promotion of epidermal keratinocytes proliferation by cell culture | 10μmol/L | Promotion rate: 126(blank 100) |
Determination of SPF of sun protection effect | 1.5% | SPF value: 30(blank 7) |
Inhibition of lipoxygenase-1 activity | IC50: 1.02μg/mL | |
Inhibition of NF-kB cell activity | 5μmol/L | Inhibition rate: 33.9% |
Activation promotion of Peroxisome Proliferator Activated Receptor (PPAR) | 50μmol/L | Promotion rate: 139(blank 100) |
7. Plamed Resveratrol Characteristic
- Plamed doesn’t add cheap synthesized Resveratrol. Plamed Resveratrol has a higher activity.
- The process has been upgraded many times, so Plamed Resveratrol has a cost advantages.
- Plamed Resveratrol’s color is whiter, and it is more suitable for cosmetics.
8. Cosmetics Grade Resveratrol Application & Attention
Resveratrol is widely used in anti-aging, anti-oxidation, whitening, sun protection, anti-allergic cosmetics.
Attention:
- Resveratrol is often used in combination with various kinds of vitamins, such as vitamin C, vitamin E, and retinoic acid.
- Resveratrol is unstable under alkaline conditions (pH>10) and it will turn pink or red.
- Resveratrol can be used in combination with AHA to reduce irritation of AHA on skin.
Resveratrol application cases in major cosmetic brands in the world:
Country | Brand | Product |
Japan | Shiseido | White Lucent Total Brightening Serum
White Lucent Microtargeting Spot Corrector |
Dr. Ci: Labo | Aqua-Collagen-Gel Enrich-Lift EX | |
Hada Labo | Whitening Cream
Double Skin Whitening And Moisturizing Cleanser Soft And Clearing Cleanser |
|
Skin Advanced | Skin Advanced Moisturizing Emulsion
Skin Advanced Moisturizing Spray Skin Advanced Gel |
|
UAS | Paula’s Choice | RESIST Super-Light Daily Defense SPF 30
Resist Weightless Advanced Repairing Toner |
Topix | Topix Replenix Restorative Nighttime Bio-Therapy | |
Topix Replenix Power of Three Serum | ||
Wei to go beauty | Miracle 3RX Age Shiel Serum | |
Canada | The Ordinary | The Ordinary Resveratrol 3% + Ferulic Acid 3% |
China | Genuine Namir | Snow Rose Crystal Whitening Essence |
JUNPING | JUNPING Brightening Firming Eye Cream | |
PURID | PURID Overnight Refirming Essence | |
France | Caudalie | Caudalie Resveratrol Firming Serum
Caudalie Resveratrol Night Infusion Cream |
S triVectin-SD | StriVectin Eye Concentrate for Wrinkles | |
Lancome | Lancome Renergie French Lift Night Cream | |
Korea | Laneige | Laneige White Plus Renew Original Essence |
Switzerland | La Prairie | La Prairie White Caviar Illuminating Moisturizing Cream
La prairie White Caviar Illuminating Eye Cream |
9. Cosmetics Grade Resveratrol Reference Formula
Anti-wrinkle emulsion:
Ingredient | Content(%) | Ingredient | Content(%) |
Resveratrol | 2.0 | Triethanolamine | 0.15 |
Glycolic acid | 8.0 | 1,3-butanediol | 3.0 |
Mineral oil | 4.0 | Xanthan gum | 0.3 |
1,3-Dimethyl-2-imidazolidinone | 1.0 | Fragrance | Appropriate |
Cetyl alcohol polyoxyethylene (10) ether | 4.0 | Butylparaben | 0.01 |
Cetanol | 4.0 | Refined water |
Add to 100 |
10. Cosmetics Grade Resveratrol Safety
- Resveratrol is evaluated as Generally Recognized as Safe (GRAS) by USA’s Food and Drug Administration (FDA).
- Cosmetic, Toiletry &Fragrance Association (CTFA) has specified Resveratrol as a cosmetics ingredient.
- Resveratrol is listed on The International Catalogue of Chinese Cosmetic Raw Materials Standards in 2010 issued by CAFFCI and On the Announcement of Name List of Cosmetics Raw Material published by CFDA in 2014. No reports show its insecurity.
11. Packing and Storage
Package: Packed in 25kg paper drums with two plastic bags inside.
Storage: Stored in a cool dry place and away from direct sunlight and oxidizing agents.
Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.
As a professional Cosmetics Grade Resveratrol manufacturer, Plamed have been constantly upgrading the production process. We firmly believe that good Cosmetics Grade Resveratrol and good Resveratrol price will help customers make good terminal products and help customers win a lasting and broad market.
Other Skin-whitening Product List
NO. | Product Name | Product ID | Specification | Product Image |
---|---|---|---|---|
01 | Arbutin | PMB0101 PMB0102 | Alpha 99.5% Beta 99.0% | |
02 | PCR Glabridin | PMB0705PCR | 10% | |
03 | Kojic Acid Dipalmitate | PMB0801 | 99% | |
04 | D-alpha Tocopherol Acetate | PMB0901 PMB0902 | 700IU 1300IU | |
05 | Bakuchiol | PMKZ1501 | 98% | |
06 | Grape seed extract | PMB1401 | 95%OPC | |
07 | Ellagic Acid | PMB0401 | 98% | |
08 | Glabridin | PMB0705,PMB0702 PMB0703,PMB0704 | 10%,40% 90%,98% | |
09 | Glutathione | PMB1601 | 98% | |
10 | Ascorbic Acid 2-Glucoside | PMB1801 | 98% | |
11 | Phloretin | PMB0301 | 98% | |
12 | Lycopene | PMB1101 | 80% | |
13 | Resveratrol | PMB0501 | 98% | |
14 | Green Tea Extract | PMB1501, PMB1502, PMB1503 | 95% EGCG, 70% oil-soluble polyphenols, 98% water-soluble polyphenols | |
15 | Luteolin | PMB1301 | 98% | |
16 | Chrysin | PMB1001 | 99% | |
17 | Puerarin | PMB1201 | 98% | |
18 | Escin | PMM0301 | 20%, 98% | |
19 | Tetrahydrocurcumin | PMB0201 | 98% | |
20 | Nicotinamide | PMB1501 | 99% | |
21 | Curcumin | PMB2501 | 10% | |
22 | Rhodiola-crenulata-extract | PMB2401 | 2% Salidroside |