1. Oily Skin Ingredient PMOil-control® Pueraria Introduction
Pueraria lobata is one of the most common traditional Chinese medicines, and has a long history of clinical use. It was first recorded in the “Shen Nong’s Materia Medica” of the Han Dynasty in ancient China. Pueraria lobata is rich in a variety of natural plant compounds, it’s a beneficial source of isoflavone, genistein, and daidzein that have been show to improve signs of ageing. In 1959, Shibata et al. first reported puerarin as a unique component of Pueraria lobata. Song et al. have reviewed in detail the research on the chemical components of Pueraria lobata published before 2014, mainly including flavonoids, triterpenes, coumarins, saponins and other compounds. Studies have shown that Pueraria lobata has the functions of promoting cerebrovascular and retinal blood flow, and spasmolyzing, anti-cancer, lowering blood sugar and blood pressure, antioxidant, etc.. Plamed found that Pueraria lobata has a strong inhibitory effect on 5α-reductase. Therefore, we develop PMOil-control® Pueraria which is a natural cosmetic raw material for oil control.
| Product Name | INCI Name | Content | |
| PMOil-control® Pueraria
|
PUERARIA LOBATA EXTRACT | 10%~40% | |
| HYDROXYPROPYL CYCLODEXTRIN | 60%~90% | ||
| Minimal Package | Minimal Order Quality | ||
| 1KG | 1KG | ||
2. Botanical Source
Pueraria lobata, also named Kudzu, is the dry root of Leguminosae family. It mainly grows in Henan, Shaanxi, Anhui, Zhejiang of China. Shaanxi is the largest producer of pueraria in the north. The plant contains many medicinal ingredients. Kudzu root is a homologous plant of medicine and food, which has a history of more than 3000 years in Chinese folk food, and has a long history of thousands of years as a precious Chinese medicinal material. It is an important medicinal material for clearing heat and detoxifying, and protecting liver and kidney. It can be used in medicine, health care products and cosmetics.
3. Technical Data Sheet
| Items | Specification |
| Part used | Root |
| Organoleptic Tests | |
| Appearance | Off white to white powder |
| Odor | Characteristic |
| Taste | Characteristic |
| Physical Characteristics | |
| Moisture | ≤10.0% |
| Ash content | ≤7.0% |
| Pueraria flavones | ≥15% |
| Heavy Metals | |
| Pb | ≤10ppm |
| As | ≤2ppm |
| Hg | ≤1ppm |
| Cd | ≤5ppm |
| Microbiological Tests | |
| Total of bacteria | ≤1000cfu/g |
| Yeast & mold | ≤100cfu/g |
| Pseudomonas aeruginosa | Not detected |
| Staphylococcus aureus | Not detected |
| Heat-resistant escherichia coil | Not detected |
4. PMOil-control® Pueraria Mechanism & Function
- Oil-control
1. Inhibition of 5α-reductase
5α-reductase is a membrane protease that relies on reduced coenzyme II (NADPH). It is an important androgen metabolism enzyme in the skin. It can irreversibly convert testosterone into dihydrotestosterone (DHT). DHT is the most active androgen and can induce excessive sebaceous glands. Secrete oil. Therefore, reducing DHT levels by inhibiting 5α-reductase activity can effectively alleviate excessive oil secretion by sebaceous glands.
Plamed also submitted for testing the 5α-reductase inhibition rate of PMOil-control® Pueraria and PCA zinc.
The test results of sample PMOil-control® Pueraria are as follows:
| Groups | Inhibition rate of 5α-reductase | P value |
| Blank control group | 0.00 | / |
| Positive group | 69.36 | ＜0.001 |
| 1.0% PMOil-control® Pueraria | 96.71 | ＜0.001 |
| 0.5% PMOil-control® Pueraria | 75.78 | ＜0.001 |
| 0.1% PMOil-control® Pueraria | 57.83 | ＜0.001 |
The test results of sample PCA zinc are as follows:
| Groups | Inhibition rate of 5α-reductase | P value |
| Blank control group | 0.00 | / |
| Positive group | 69.36 | ＜0.001 |
| 1.0% PCA zinc | 80.40 | ＜0.001 |
| 0.5% PCA zinc | 46.29 | ＜0.001 |
Test results show that 1% PMOil-control® Pueraria has an inhibitory rate of 96.71% on 5α-reductase, which is better than the mainstream synthetic ingredient PCA zinc on the market.
2. Inhibition of lipid droplets
PMOil-control® Pueraria can significantly reduce the content of lipid droplets in human sebaceous gland cells, revealing its significant oil control effect.
| Groups | Relative IOD value | SD | P-value | Inhibition rate |
| BC | 1.00 | 0.02 | / | / |
| NC | 2.49 | 0.14 | 0.002## | / |
| PC | 1.05 | 0.02 | 0.003** | / |
| PMOil-control® Pueraria 0.008% | 1.47 | 0.02 | 0.008** | 40.96% |
| PMOil-control® Pueraria 0.016% | 1.23 | 0.02 | 0.005** | 50.6% |
| PMOil-control® Pueraria 0.25% | 1.12 | 0.05 | 0.001** | 55.02% |
| PMOil-control® Pueraria 0.5% | 1.07 | 0.02 | 0.004** | 57.03% |
The inhibition rates of PMOil-control® Pueraria on the formation of lipid droplets in human sebaceous gland cells were 40.96%, 50.6%, 55.02% and 57.03% at the concentrations of 0.008%, 0.016%, 0.25% and 0.5%, respectively.
5. PMOil-control® Pueraria Advantages
- Strong oil control efficacy: at the same concentration, the inhibition rate of PMOil-control®Pueraria on 5α-reductase exceeds PCA zinc.
- It can be 100% dissolved in water at room temperature.
6. PMOil-control® Pueraria Application & Dosage
| Application | Recommended Dosage |
| Masque, cleanser, lotion, toner, serum, essence, cream, etc. | 0.1%~1.0% |
7. PMOil-control® Pueraria Safety
- PUERARIA LOBATA EXTRACTis CFDA (China Food and Drug Administration) has approved the use of cosmetic ingredients.
- International Cosmetic Raw Material Standard Chinese Name Directory (2010 edition) has included PUERARIA LOBATA EXTRACT.
- Human skin patch test:the safety of PMOil-control® Pueraria was tested according to the “Safety Technical Specifications for Cosmetics” (2015 Edition). The results showed that 30 people had no skin irritation in 48 hours after using the sample PMOil-control® Pueraria.
- PMOil-control®Pueraria has no irritation at the concentration of 3%, based on vitro eye irritation test.
8. PMOil-control® Pueraria Stability
Plamed done the stability test of PMOil-control® Pueraria for months, it showed that its water solution and powder for each batch is stable.
Also, PMOil-control® Pueraria has good pH stability in the range of 4-6.
9. Packing and Storage
Package: Packed in 25kg paper drums with two plastic bags inside.
Storage: Stored in a cool and dry place and away from direct sunlight and oxidizing agents.
Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.
As a professional Oily Skin Ingredient PMOil-control® Pueraria manufacturer, Plamed have been constantly upgrading the production process. We firmly believe that good Oily Skin Ingredient PMOil-control® Pueraria and good Oily Skin Ingredient PMOil-control® Pueraria price will help customers make good terminal products and help customers win a lasting and broad market.
