1. PMAnti-dandruff® 9986 Overview
Where to buy Oil-control & Anti-dandruff Natural Ingredient PMAnti-dandruff® 9986 with reasonable price and high quality? Where to find good information of wholesale Oil-control & Anti-dandruff Natural Ingredient PMAnti-dandruff® 9986? As the professional Oil-control & Anti-dandruff Natural Ingredient PMAnti-dandruff® 9986 manufacturer, Plamed is your best choice.
Today, scalp and hair health is as important to people as the skin on their face, and most men are more concerned about their hair. 78% of consumers prefer hair care products with natural, gentle formulas, and 80% are concerned about anti-dandruff ingredients in hair care products.
For this reason, Plamed has developed a natural and powerful anti-dandruff ingredient: PMAnti-dandruff® 9986, which is a combination of Pueraria lobata extract and magnolia officinalis bark extract. The traditional Chinese medicine magnolia officinalis refers to the dried root and branch bark of the plant. Magnolia officinalis has a strong antibacterial effect against staphylococcus and streptococcus. Pueraria lobata is also one of the most common Chinese medicines in China with a long history of clinical use. Pueraria lobata was first reported as a unique constituent of Pueraria Mirifica by Shibata et al. in 1959. Song et al. have provided a detailed overview of the studies published before 2014 on the chemical constituents of Pueraria Mirifica which are mainly compounds of the flavonoids, triterpenoids, coumarins, and saponins class. Studies have shown that pueraria lobata has the functions of promoting cardiovascular and retinal blood flow, diastolic smooth muscle antispasmodic, anticarcinogenic, inducing hypoglycemic, hypotensive, antioxidant, antipyretic, antialcoholic, improving memory and enhancing immunity. It has been found by Plamed that pueraria lobata extract has a strong inhibitory effect on 5α-reductase.
PMAnti-dandruff® 9986 is a natural cosmetic ingredient researched by Plamed for anti-dandruff and oil control, which has a broad application prospect in hair care field.
| Product Name | INCI Name | ||
| PMAnti-dandruff® 9986 | PUERARIA LOBATA EXTRACT, MAGNOLIA OFFICINALIS BARK EXTRACT, HYDROXYPROPYL CYCLODEXTRIN |
||
| Product ID | Specification | Minimal Package | Minimal Order Quality |
| PMAD0101 | 6% magnolol 10% puerarin |
1KG | 1KG |
2. PMAnti-dandruff® 9986 Botanical Source
Pueraria lobata is one of the most common Chinese medicines in China with a long history of clinical use. Pueraria lobata is listed in the “Catalog of Substances Traditionally Used as Both Food and Traditional Chinese Medicine” issued by the National Health and Wellness Commission of the People’s Republic of China. Pueraria lobata is rich in a variety of natural plant compounds, and studies on the chemical composition of pueraria lobata have focused on flavonoids, triterpenes, coumarins, saponins and other compounds. Studies have shown that pueraria lobata has the functions of promoting cardiovascular and retinal blood flow, diastolic smooth muscle antispasmodic, inducing hypoglycemic, hypotensive, antioxidant, antipyretic and antialcoholic, improving memory and enhancing immunity. Plamed found that pueraria lobata has a strong inhibitory effect on 5α-reductase.
Mangnolia officinalis is a traditional Chinese herb that is commonly used in Chinese medicine formulas for its effects of drying dampness, eliminating phlegm, and lowering qi to remove mites. It also has anti-microbial and anti-inflammatory properties; Mangnolia officinalis has a broad-spectrum antibacterial effect and inhibits certain viruses.
3. Technical Data Sheet
| Items | Specification |
| Magnolol | ≥6% |
| Puerarin | ≥10% |
| Organoleptic Tests | |
| Appearance | Powder |
| Color | White |
| Odor | Characteristic |
| Physical Characteristics | |
| Moisture | ≤10.0% |
| Ash content | ≤7.0% |
| Heavy Metals | |
| Pb | ≤10ppm |
| As | ≤2ppm |
| Hg | ≤1ppm |
| Cd | ≤5ppm |
| Microbiological Tests | |
| Total of bacteria | ≤1000cfu/g |
| Yeast & mold | ≤100cfu/g |
| Pseudomonas aeruginosa | Not detected |
| Staphylococcus aureus | Not detected |
| Heat-resistant escherichia coil | Not detected |
4. Causes of Dandruff
① Excessive oil secretion
Oil imbalance is closely related to increased dandruff. Excessive scalp oil secretion, resulting in oxidative damage to the scalp, easily triggered seborrheic dermatitis. A large amount of sebaceous gland lipids in the scalp stratum corneum may destroy the organizational structure of the lipid between the surface cells, prompting skin flaking, and facilitating the colonization of Malassezia in the stratum corneum.
② Microecological imbalance
A variety of microorganisms are distributed on the human scalp, mainly composed of staphylococci, propionibacteria and Malassezia. When the scalp micro-ecological imbalance, dandruff scalp Malassezia on the scalp has 10 times as many as the normal scalp. Originally, Malassezia spp. made up only a small portion of the scalp, with the dominant flora being Propionibacterium acnes. The imbalance between the rapid proliferation of Malassezia and the ratio of Propionibacterium acnes is the source of scalp problems.
③ Damaged scalp barrier
Long-term damage to the scalp (e.g., excessive cleaning, ironing, scratching, overpopulation of P. acnes, etc.) stimulates the signaling pathway of inflammation deep in the skin, leading to inflammation of the scalp, a series of barrier dysfunctions that lead to the abnormal differentiation and proliferation of epidermal cells and cause dandruff.
5. PMAnti-dandruff® 9986 Benefits
- Oil control
5α-reductase is a membrane protease dependent on reduced coenzyme II (NADPH), an important androgen metabolizing enzyme in the skin, which can irreversibly convert testosterone (T) to dihydrotestosterone (DHT), which is the most active androgen and can induce the sebaceous glands to overproduce sebum. DHT is the most active androgen, which can induce sebaceous glands to overproduce oil. Reducing the level of DHT by inhibiting 5a-reductase activity can effectively relieve the excessive secretion of sebum by sebaceous glands and control the oil. The 5a-reductase inhibition rate of the test product was used as an indicator to evaluate the oil-control effect of the test product.
Test result: the inhibition of 5α-reductase by 1% concentration of PMAnti-dandruff® 9986 was 86.6%.
- Inhibit malassezia furfur
PMAnti-dandruff® 9986 at 0.15% inhibited malassezia furfur by 99.99%, which is equivalent to the anti-dandruff mainstays selenium sulfide and OCT (Octopirox).
| Sample | Test concentration | Inhibition rate to malassezia furfur |
| Selenium sulfide | 0.15% | >99.99% |
| OCT (Octopirox) | >99.99% | |
| PMAnti-dandruff® 9986 | >99.99% |
6. Application & Reference Dosage
| Application Product | Reference Dosage |
| Leave-on cosmetics | ≤3.8% |
| Wash-off cosmetics | ≤0.19% |
7. PMAnti-dandruff® 9986 Safety
- Pueraria Lobata Extract and Magnolia Officinalis Bark Extract areall listed in Announcement on the List of Names of Used Cosmetic Raw Materials issued by China NMPA in 2014.
8. Packing and Storage
Package: 1kg/bag, outer package is paper box or paper drum.
Storage: Stored in a cool and dry place and away from direct sunlight and oxidizing agents.
Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.
Plamed Vision: Become the leader of natural cosmetic ingredients for sensitive skin.
As a professional oil-control and anti-dandruff natural ingredient PMAnti-dandruff® 9986 manufacturer, Plamed have been constantly upgrading the production process. We firmly believe that good oil-control and anti-dandruff natural ingredient PMAnti-dandruff® 9986 and good oil-control and anti-dandruff natural ingredient PMAnti-dandruff® 9986 price will help customers make good terminal products and help customers win a lasting and broad market.
