1. Ceramide Overview
Ceramide is the main component of the lipids among cells of the most lateral cuticle in human skin. It is a water-soluble lipid substance. The structure is similar to that of substance that makes up the cuticle layer of the skin. It can quickly penetrate into the skin and combine with the water in the cuticle layer, then forming a network structure that locks moisture. Currently, as a moisturizer. Both Ceramide 3 and Ceramide 3B belong to the category of Ceramide NP. The fatty acid part is stearic acid/oleic acid, which belongs to non-hydroxyl fatty acid (N); and it is constructed by amide bond with phytosphingosine (P). Both are belongs to ceramide NP. So Ceramide NP is not a single substance, but is a general term for a large group of ceramides that have a similar structural principle. Plamed mainly supply Ceramide 3B, it is usually used in cosmetics product for moisturizing, repairing skin, and anti-inflammation.
Product Name | CAS Number | INCI | |
Ceramide NP | 100403-19-8 | Ceramide NP | |
Molecular Structure | |||
Product ID | Specification | Minimal Package | Minimal Order Quality |
PMS0101 | Purity≥95% | 1kg | 1kg |
2. Ceramide Manufacturer Specifications
Items | Specifications |
Assay (HPLC-UV,
external standard method) |
A≥ 85.0% |
A+B+C+D≥ 95.0% | |
Purity (HPLC-UV,
area normalization method) |
A≥ 85.0% |
A+B+C+D≥ 95.0% | |
Organoleptic | |
Appearance | white to off-white powder |
Physical Characteristics | |
Melting point | 98℃~108℃ |
Loss on drying | ≤2.0% |
Residue on ignition | ≤0.5% |
Residual Solvents | |
Menthol | ≤3000ppm |
Ethyl oleate | ≤2000ppm |
Heavy Metals | |
Heavy metals | ≤20ppm |
Microbiological Tests | |
Total plate count | ≤500cfu/g |
Yeast & mold | ≤100cfu/g |
3. Ceramide Benefits
- Moisturizing
Ceramide has a strong ability to associate water molecules. It can maintain moisture in the skin by forming networks in the stratum corneum. Therefore, Ceramide is capable of retaining moisture and locking water.
- Anti-oxidation
The rate of lipid synthesis decreases in the process of skin aging, and the content of Ceramide in the stratum corneum reduces. Replenishing Ceramide to skin can enhance the content, and then solve the problems such as dry, peeling and rough skin. At the sametime, Ceramide can increase the thicknessof cuticle and promote the skin’s ability to remain water. Also it is effective to reduce wrinkles, strengthen skin elasticity, and delay skin aging.
4. Plamed Ceramide Characteristics
- High purity, less impurities. The solution in methanol is colorless and transparent
5. Application and Reference Amount
Ceramide is widely used in cosmetics, such as lotion, cream, essence, etc. It works well with linolenic acid,hyaluronic acid and vitamins.
Products Name | Reference Amount |
Ceramide 3B | 0.01-5% |
Ceramide application examples in cosmetic brands around the world
Country | Brand | Product |
USA |
Elizabeth arden |
Ceramide gold ultra restorative capsules,
Night skin firming cream |
Paula’s Choice |
Ceramide-enriched firming moisturizer,
Moisture renewal oil booster Skin balancing oil-reducing cleanser |
|
Skinceuticals | Triple Lipid Restore 2:4:2 | |
Skinmedica TNS | Ceramide Treatment Cream | |
Cerave | Moisturizing Lotion | |
IT Cosmetics | Confidence in a Cream | |
Topix SRS | Neuramide repair essence | |
Albion | Eclafutur Cell repair essence | |
DHC | Ceramide Cream | |
Curel | Skin Moisturizer,
Makeup Cleansing Gel |
|
Japan | Tunemakers | Ceramide Blending 200 Essence |
Singapore | Skin Inc. | Ceramide Serum |
China | BOBI Water | Ceramide repair cream |
6. Ceramide Uses in Cosmetics Formula
- Avoid long time high temperature heating, in order to prevent discoloration.
- pH value should be controlled at 5.5-7.0
- Add it in the oil phase, involved in emulsification, fully dissolved.
- Storage conditions: sealed and refrigerated away from light.
7. Ceramide Reference Formula
Moisturizing essence
Ingredient | Content | Ingredient | Content |
Ceramide | 30 mg | Hyaluronic acid | 50 mg |
Pine bark extract | 25 mg | Astaxanthin | 4 mg |
Coconut milk | 300 mg | Lutein | 5 mg |
Vitamin C | 60 mg |
Whitening cream
Ingredient |
Content (%) |
Ingredient |
Content (%) |
Ceramide | 0.2 | Sorbitan palmitate | 6.0 |
Sunflower oil | 9.0 | Preservative | 0.35 |
Glyceryl stearate | 4.0 | Fully hydrogenated squalane | 5.0 |
Glycerin | 5.0 | Fragrance | 1.0 |
Purified water | Add to 100 | Diisopropyl cyclohexane | 7.0 |
Ceramide toner
Ingredient | Content (%) | Ingredient | Content (%) |
Ceramide | 0.2 | Tea tree essential oil | 2 |
Nano-silica | 7 | Dipropylene glycol | 6 |
Bisabolol | 0.5 | Butylphenyl methyl formaldehyde | 3 |
Allantoin | 4 | Dipotassium glycyrrhizate | 1.5 |
Salicylate | 3 | Sodium hyaluronate | 3 |
Nicotinamide | 6 | Compound polypeptide | 3 |
Vitamin E | 2 | Nano-selenium | 3 |
Water | 65 | Functional extract | 5 |
Resveratrol | 0.06 | Lemongrass extract | 0.5 |
Preservative | 0.05 |
8. Ceramide Safety
On the Announcement of Name List of Cosmetics Raw Material published by China Food and Drug Administration in 2014, and The Catalog Of the International Cosmetics Raw Material Standard English Name issued by CTFA and CAFFCI in 2010 both have recognized Ceramide NP as a raw material of cosmetics. There is no report showing its insecurity for external use.
9. Packing and Storage
Package: Packed in 1kg aluminum foil bag, or 25kg paper drums with two plastic bags inside.
Storage: Stored in a cool dry place and away from direct sunlight and oxidizing agents.
10. Related Reading
Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.
As a professional Ceramide manufacturer, Plamed have been constantly upgrading the production process. We firmly believe that good Ceramide and good Ceramide price will help customers make good terminal products and help customers win a lasting and broad market.