Plamed | Combining advanced formulation science, molecular engineering, and biotechnology to develop high-performance functional ingredient solutions.
Skin irritation perception involves multiple sensory receptors beyond TRPV1. Traditional single-target approaches cannot fully address the complex process of skin irritation.
Plamed pioneered the introduction of Action Potential (AP)—the common convergence point of skin irritation signals—into cosmetic anti-irritation research, establishing a comprehensive AP neural anti-irritation pathway system that delivers broad-spectrum soothing benefits.
Neural anti-irritation active extracted from kava peper root, PMSoothe® Kava97 is developed based on AP nerve anti-irritation pathway research. It modulates TRPV1 expression and action potential transmission by targeting the reception and transduction of irritation signals, delivering comprehensive neural anti-irritation benefits to skin. With broad-spectrum anti-irritation performance, it is compatible with chemical exfoliation, sensitive skin care and scalp care formulations.
