Oily Skin Ingredient PMOil-control® Pueraria

• Oil-control

1. Inhibition of 5α-reductase

5α-reductase is a membrane protease that relies on reduced coenzyme II (NADPH). It is an important androgen metabolism enzyme in the skin. It can irreversibly convert testosterone into dihydrotestosterone (DHT). DHT is the most active androgen and can induce excessive sebaceous glands. Secrete oil. Therefore, reducing DHT levels by inhibiting 5α-reductase activity can effectively alleviate excessive oil secretion by sebaceous glands.

Plamed also submitted for testing the 5α-reductase inhibition rate of PMOil-control® Pueraria and PCA zinc.

The test results of sample PMOil-control® Pueraria are as follows:

The test results of sample PCA zinc are as follows:

Test results show that 1% PMOil-control® Pueraria has an inhibitory rate of 96.71% on 5α-reductase, which is better than the mainstream synthetic ingredient PCA zinc on the market.

2. Inhibition of lipid droplets

PMOil-control® Pueraria can significantly reduce the content of lipid droplets in human sebaceous gland cells, revealing its significant oil control effect.

The inhibition rates of PMOil-control® Pueraria on the formation of lipid droplets in human sebaceous gland cells were 40.96%, 50.6%, 55.02% and 57.03% at the concentrations of 0.008%, 0.016%, 0.25% and 0.5%, respectively.

• ·Strong oil control efficacy: at the same concentration, the inhibition rate of PMOil-control®Pueraria on 5α-reductase exceeds  PCA zinc.
• ·It can be 100% dissolved in water at room temperature.

• PUERARIA LOBATA EXTRACTis CFDA (China Food and Drug Administration) has approved the use of cosmetic ingredients.
• International Cosmetic Raw Material Standard Chinese Name Directory (2010 edition) has included PUERARIA LOBATA EXTRACT.
• Human skin patch test:the safety of PMOil-control® Pueraria was tested according to the “Safety Technical Specifications for Cosmetics” (2015 Edition). The results showed that 30 people had no skin irritation in 48 hours after using the sample PMOil-control® Pueraria.
• 
• PMOil-control®Pueraria has no irritation at the concentration of 3%, based on vitro eye irritation test.
• 
  

Package: Packed in 25kg paper drums with two plastic bags inside.

Storage: Stored in a cool and dry place and away from direct sunlight and oxidizing agents.

Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.

Q：Can PMOil-control® Pueraria provide an official “Cruelty-Free” (no animal testing) statement?

A: Regrettably, we cannot provide this statement. To comply with rigorous regulatory safety standards for cosmetic ingredients both domestically and internationally, this material underwent mandatory full-scale safety and toxicological assessments. Since these legally required toxicological evaluations inevitably involve animal studies, a cruelty-free statement cannot be issued.

Q：How does PMOil-control® Pueraria achieve a high concentration of puerarin while maintaining excellent water solubility?

A: Extracting high-purity puerarin (up to 80%) is a highly mature traditional process in China. To overcome its inherent dissolution limits in formulations, Plamed utilizes a proprietary supramolecular encapsulation technology. This ensures a high content of active puerarin while significantly enhancing its water solubility and stability in aqueous systems.

Q：Clinical data shows a tested concentration of 0.5%. When adding 0.5% Supramolecular Pueraria to a formula, is it necessary to compound it with other anti-acne ingredients?

A: Clinical tests show that 0.5% PMOil-control® Pueraria alone delivers excellent results in human oil control and acne reduction. Since its primary mechanism targets the root cause of excess sebum (oil control), and acne is often triggered by multi-factorial causes, we recommend synergistically compounding it with exfoliating agents (e.g., Salix Alba Bark Extract), anti-inflammatory, or antibacterial ingredients (e.g., Magnolia Officinalis Bark Extract) for a comprehensive, fast-acting anti-acne solution.

Q：What is the difference between the commonly known “molecular imprinting technology” and Plamed’s “supramolecular capture technology”?

A: The core mechanisms and targeting scopes differ: molecular imprinting technology focuses on the precise identification and extraction of a “single specific molecule.” In contrast, Plamed’s supramolecular capture technology efficiently enriches a “class of functional components sharing specific physicochemical properties,” such as low-polarity molecular groups with molecular weights between 400–600, linear structure or a number of fused rings around 5.

Q：What specific components are included in the Pueraria flavonoids of PMOil-control® Pueraria? Which one drives the core efficacy?

A: Pueraria flavonoids generally consist of four core flavonoid components. In our PMOil-control® Pueraria, through directional capture and supramolecular processing, the primary active ingredient driving the core oil-control and anti-acne efficacy is high-purity Pueraria.

Q：Is PMOil-control® Pueraria patented?

A: Yes. The core encapsulation technology and application of this product have been officially submitted to the National Intellectual Property Administration as an invention patent application, which is currently under official review and pending authorization.