Name: Tetrahydrocurcumin
Brand: Plamed Green Science
SKU: –

Overview

Tetrahydrocurcumin (THC) is the most active and principal intestinal metabolite of curcumin. It comes from hydrogenated curcumin that is from turmeric root. THC has a great effect of skin-whitening. Also it can prevent the production of free radicals, and eliminate free radicals that have formed. So, it has obvious antioxidant effects, such as anti-aging, repairing skin, diluting pigment, removing freckle, and so on. Nowadays, THC has been widely used as a natural whitening agent, and it enjoys vast potentials in cosmetics industries.

Product Name	CAS Number	INCI Name
Tetrahydrocurcumin	36062-04-1	Tetrahydrocurcumin
Molecular Weight	Molecular Formula	Molecular Structure
C21H26O6	372.2g/mol
Product ID	Specificcation	Minimal Package	Minimal Order Quantity
PMB0201	98%	1KG	1KG

Source

Turmeric (Latin name: Curcuma longa L.) is a perennial herb with a well-developed root of ginger family. It’s also known as Yujin, Baodingxiang, Madian, Huangjiang, etc. Leaves are oblong or elliptic, and corolla is yellowish. It can be found in several Chinese provinces, including Taiwan, Fujian, Guangdong, Guangxi, Yunnan, and Tibet; it is also widely cultivated in East and South-east Asia. Roots are the commercial sources of the traditional Chinese medicine “turmeric”. People pick out impurities in turmeric’s root, soak in water, then slice, and dry it. It can resolve stasis, promote menstrual circulation and relieve pain.

Curcumin Comparison

Tetrahydrocurcuminoids	Curcumin
Source&Specification	Hydrogenated derivatives of curcumin. The market specification is 98%	Extracted from the rhizome of turmeric. The market specification is 95%
Color	White	Yellow
Molecular structure
Molecular structure	Tetrahydrocurcumin’ structure is without unsaturated C=C compared to that of curcumin, so it lacks the conjugate double bonds that chromophore needs. Therefore, in terms of color, Tetrahydrocurcumin changes from yellow of curcumin to white powder.
Property	High stability, more antioxidant. Bioavailability is higher than curcumin	Poor solubility, the structure is relatively unstable, low bioavailability
Function	Tetrahydrocurcumin is more stable and more antioxidant than curcumin, so it is more bioavailable and widely used, but the basic efficacy of both is the same: anti-inflammation, anti-oxidation, skin-whitening, remove freckle, promote wound repair（It is mainly shown in promoting the production of β-transformed growth factor (TGF-β) and collagen and the regeneration of epidermal cells.） Tetrahydrocurcumin’s IC50 is 0.000492 ppm (curcumin is 0.730ppm, kojic acid is 9.14ppm). whitening effect of Tetrahydrocurcuminis much betterand its white color is more suitable for making cosmetics.
Application	High-end cosmetics Its whitening effect is even better than that of Arbutin	Health care and functional food.

Manufacturer Specifications

Product Name	Specification	Color
Tetrahydrocurcumin	98%	Off White or yellowish

Items	Specifications
Identification	NMR
Assay (Enol form and keto form)	Tetrahydrocurcumin≥98% HPLC
Appearance	Off white or yellowish powder
Melting point	91~97℃
Moisture	≤1.00%

Manufacturer Flow Chart

Benefits

Skin-whitening

Tetrahydrocurcumin can inhibit tyrosinase effectively. It has great potency of antioxidant and ability to capture free radicals, which are the main reason for its skin-whitening effect. In some beauty industries, people apply the mixture of THC powder, milk and egg white on the face. As a result, the face became more white significantly after two weeks. uploaded image

Anti-aging and anti-wrinkles

Scientific studies have shown that THC is effective to protect cellular membrane damage that is caused by lipid peroxidation. And its antioxidant effect is better than other hydrogenated curcumin so that it can be against wrinkles availably and prevent skin aging.

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Anti-inflammatory effect

Turmeric is commonly used as a traditional medicine to heal wounds and remove scars in India. And THC extracted from turmeric has a strong anti-inflammatory and antibacterial effect, which can effectively reduce pain as well as swelling and repair skin. It has obvious functions to cure slight burn wound, skin inflammatory and scars.

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Characteristic

1. Good stability in heat, mechanical and PH; no color change.
2. Small particle size with even distribution: the product after dispersing is clear and transparent.
3. Easy to absorb: promote active substances to absorb; have a potent bioactivity.
4. More white color than other companies’. Better choice as raw material of cosmetics.

Application & Dosage

THC is widely used in various skin care products of skin-whitening, freckle, and anti-oxidation, such as creams, lotions and essence.

Specification	Reference Dosage
Tetrahydrocurcumin98%	1%-4%

Application cases of Tetrahydrocurcumin in cosmetics at home and abroad:

Country & Brand

Product

Main ingredient

Function

Spain

Endocare

Eye gel

Tetrahydrocurcumin

Vitamin E、Matrixyl

Anti-oxidant, relieve skin inflammation, soothe the skin around the eyes, make the skin thinner and smoother.

Reference Formula

Whitening Lotion：

	Ingredient	Content	Ingredient		Content
Group A	Tetrahydrocurcumin	46-50	Guar gum		48-52
	Aloe vera extract	50-54	Papaya extrac		46-50
	Sesame oil	50-54	Paeoniflorin		46-50
	Shea butter	50-54	Ophiopogon root extract		46-50
	Black bean estrogen	46-50	Nigella extract		50-54
	Theobroma oil	50-54	Codium tomentosum extract		46-50
	D- panthenol	46-50	1,2- Capryl glycol		50-54
	Vitamin C	52-56	Sorbitan octanoate		46-50
	Glutathione	50-54
	Water	1000-2000	Lubrajel oil	46-50
	Blackberrglily Rhizome Extract	50-54

Preparation method：

Add Group A ingredients to water, use ultrasonic high-speed dispersion. The ultrasonic frequency is 20-40 KHZ, Dispersion speed is about 5000-5400r/min, The dispersal time is 30-60min.
Add Lubrajel oil, then use ultrasonic high-speed dispersion, the ultrasonic frequency is 20-35khz, the dispersion speed is about 4800-5200r/min, and the dispersion time is 30-50min.
Add Blackberrglily Rhizome Extract, use ultrasonic high-speed dispersion. The ultrasonic frequency was 20-30khz, the dispersion speed was about 4,600-4800r /min, and the dispersion time was 20-40mi. Then mix evenly the above solution to get the lotion.

Safety & Storage

Tetrahydrocurcumin Safety

THC has no side-effects when it is added into cosmetics because of its functions of antibacterial and anti-inflammatory. Instead, it can exert its effects of skin-whitening and brightening.

Packing and Storage

Packed in 25kg paper drums with two plastic bags inside.

Store it in a cool dry place away from direct sunlight and oxidizing agents

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