Plamed Vision: Become the leader of natural cosmetic ingredients for sensitive skin.
High purity, less impurities. The solution in methanol is colorless and transparent
Ceramide is the main component of the lipids among cells of the most lateral cuticle in human skin. It is a water-soluble lipid substance. The structure is similar to that of substance that makes up the cuticle layer of the skin. It can quickly penetrate into the skin and combine with the water in the cuticle layer, then forming a network structure that locks moisture. Currently, as a moisturizer. Both Ceramide 3 and Ceramide 3B belong to the category of Ceramide NP. The fatty acid part is stearic acid/oleic acid, which belongs to non-hydroxyl fatty acid (N); and it is constructed by amide bond with phytosphingosine (P). Both are belongs to ceramide NP. So Ceramide NP is not a single substance, but is a general term for a large group of ceramides that have a similar structural principle. Plamed mainly supply Ceramide 3B, it is usually used in cosmetics product for moisturizing, repairing skin, and anti-inflammation.
| Product Name | CAS Number | INCI | |
| Ceramide NP | 100403-19-8 | Ceramide NP | |
| Molecular Structure |   |
||
| Product ID | Specification | Minimal Package | Minimal Order Quality |
| PMS0101 | Purity≥95% | 1kg | 1kg |
| Items | Specifications |
| Assay (HPLC-UV,
external standard method) |
A≥ 85.0% |
| A+B+C+D≥ 95.0% | |
| Purity (HPLC-UV,
area normalization method) |
A≥ 85.0% |
| A+B+C+D≥ 95.0% | |
| Organoleptic | |
| Appearance | white to off-white powder |
| Physical Characteristics | |
| Melting point | 98℃~108℃ |
| Loss on drying | ≤2.0% |
| Residue on ignition | ≤0.5% |
| Residual Solvents | |
| Menthol | ≤3000ppm |
| Ethyl oleate | ≤2000ppm |
| Heavy Metals | |
| Heavy metals | ≤20ppm |
| Microbiological Tests | |
| Total plate count | ≤500cfu/g |
| Yeast & mold | ≤100cfu/g |
Ceramide has a strong ability to associate water molecules. It can maintain moisture in the skin by forming networks in the stratum corneum. Therefore, Ceramide is capable of retaining moisture and locking water.
The rate of lipid synthesis decreases in the process of skin aging, and the content of Ceramide in the stratum corneum reduces. Replenishing Ceramide to skin can enhance the content, and then solve the problems such as dry, peeling and rough skin. At the sametime, Ceramide can increase the thicknessof cuticle and promote the skin’s ability to remain water. Also it is effective to reduce wrinkles, strengthen skin elasticity, and delay skin aging.
Ceramide is widely used in cosmetics, such as lotion, cream, essence, etc. It works well with linolenic acid,hyaluronic acid and vitamins.
| Products Name | Reference Amount |
| Ceramide 3B | 0.01-5% |
Ceramide application examples in cosmetic brands around the world
| Country | Brand | Product |
|
USA |
Elizabeth arden |
Ceramide gold ultra restorative capsules,
Night skin firming cream |
|
Paula’s Choice |
Ceramide-enriched firming moisturizer,
Moisture renewal oil booster Skin balancing oil-reducing cleanser |
|
| Skinceuticals | Triple Lipid Restore 2:4:2 | |
| Skinmedica TNS | Ceramide Treatment Cream | |
| Cerave | Moisturizing Lotion | |
| IT Cosmetics | Confidence in a Cream | |
| Topix SRS | Neuramide repair essence | |
| Albion | Eclafutur Cell repair essence | |
| DHC | Ceramide Cream | |
| Curel | Skin Moisturizer,
Makeup Cleansing Gel |
|
| Japan | Tunemakers | Ceramide Blending 200 Essence |
| Singapore | Skin Inc. | Ceramide Serum |
| China | BOBI Water | Ceramide repair cream |
Moisturizing essence
| Ingredient | Content | Ingredient | Content |
| Ceramide | 30 mg | Hyaluronic acid | 50 mg |
| Pine bark extract | 25 mg | Astaxanthin | 4 mg |
| Coconut milk | 300 mg | Lutein | 5 mg |
| Vitamin C | 60 mg | ||
Whitening cream
|
Ingredient |
Content (%) |
Ingredient |
Content (%) |
| Ceramide | 0.2 | Sorbitan palmitate | 6.0 |
| Sunflower oil | 9.0 | Preservative | 0.35 |
| Glyceryl stearate | 4.0 | Fully hydrogenated squalane | 5.0 |
| Glycerin | 5.0 | Fragrance | 1.0 |
| Purified water | Add to 100 | Diisopropyl cyclohexane | 7.0 |
Ceramide toner
| Ingredient | Content (%) | Ingredient | Content (%) |
| Ceramide | 0.2 | Tea tree essential oil | 2 |
| Nano-silica | 7 | Dipropylene glycol | 6 |
| Bisabolol | 0.5 | Butylphenyl methyl formaldehyde | 3 |
| Allantoin | 4 | Dipotassium glycyrrhizate | 1.5 |
| Salicylate | 3 | Sodium hyaluronate | 3 |
| Nicotinamide | 6 | Compound polypeptide | 3 |
| Vitamin E | 2 | Nano-selenium | 3 |
| Water | 65 | Functional extract | 5 |
| Resveratrol | 0.06 | Lemongrass extract | 0.5 |
| Preservative | 0.05 | ||
On the Announcement of Name List of Cosmetics Raw Material published by China Food and Drug Administration in 2014, and The Catalog Of the International Cosmetics Raw Material Standard English Name issued by CTFA and CAFFCI in 2010 both have recognized Ceramide NP as a raw material of cosmetics. There is no report showing its insecurity for external use.
Package: Packed in 1kg aluminum foil bag, or 25kg paper drums with two plastic bags inside.
Storage: Stored in a cool dry place and away from direct sunlight and oxidizing agents.
Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.
A: To meet strict global standards and diverse market needs, our cosmetic ingredients are certified under major international systems:
ISO 9001:2015 (Quality Management System): Guarantees that our manufacturing processes—from raw material sourcing to final production—adhere to strict quality control standards. Ensures consistent batch-to-batch stability, which is essential for our clients in the Europe and US markets looking for premium, compliant, and reliable supply chains.
Halal Certification: Fully certified Halal, ensuring compliance with strict ingredient traceability and the absence of prohibited substances or cross-contamination.
Allows our partners to seamlessly enter and expand in the Southeast Asian (e.g., Indonesia, Malaysia) and Middle Eastern markets, meeting local regulatory mandates.
We are committed to providing fully traceable, high-quality, and compliant ingredients to support your brand’s global growth. If you need copies of our certificates or specific technical documentation (such as COA, MSDS, or compliance statements), please feel free to contact our team.
A: Yes, absolutely. Regulatory compliance and safety are our top priorities. All of our premium active ingredients have standard, internationally recognized INCI names and are fully compliant with the stringent regulations of these major markets:
European Union: Fully compliant with the EU Cosmetic Regulation (EC) No 1223/2009, including safety assessments, and banned/restricted substance lists.
United States: Formulated and manufactured in strict accordance with FDA guidelines and the latest MoCRA (Modernization of Cosmetics Regulation Act) requirements, ensuring smooth product registration and listing.
South Korea: Compliant with the regulations set by the MFDS (Ministry of Food and Drug Safety), meeting their strict standards for functional cosmetic ingredients and efficacy documentation.
Whether you are a distributor or a brand owner in Europe, the Americas, or Southeast Asia, you can seamlessly integrate our ingredients into your formulations. We provide comprehensive regulatory support dossiers (COA, TDS, MSDS, and Composition Statements) to facilitate your local product promotion.
A: Yes, we provide comprehensive efficacy dossiers for all our flagship ingredients (such as PMSoothe® Kava97, PCR® Supermolecule Escin, and PMRefresh® Willow). Our data packages include:
In-vitro (cell-based) test reports to demonstrate cellular-level activihttphttp://zhitiye.com/product/anti-irritating-cosmetics-ingredient-pmsoothe-kava97/://zhitiye.com/product/anti-irritating-cosmetics-ingredient-pmsoothe-kava97/ty and pathways.
In-vivo (human clinical) trial data to prove real-world visible results.
Safety assessments and clear Mechanism of Action (MOA) diagrams.
These rigorous, science-backed materials are designed to help our distributors easily convince formulation chemists and premium brand owners.
A: Absolutely. We support our partners’ R&D efforts through a two-step support system:
Free Samples: We provide complimentary samples for laboratory evaluation and pilot trials.
Technical & Formulation Support: To accelerate your application process, we will also provide formulation guides for you.
Our dedicated technical support team is also available to help your customers resolve challenges related to formulation stability, compatibility, and optimal dosage.
A: We empower our global distributors with a comprehensive suite of “Turn-key” Marketing Kits to minimize your promotional costs and time-to-market. Our support includes:
Technial Documentation: Product brochures, white papers, and TDS, MSDS, and COA.
Visual Materials: Ingredient videos and ready-to-use social media posters.
Market Intelligence: Detailed competitive analysis reports and trend insights.
Co-Marketing: We also attend at major international cosmetics exhibitions to boost local brand awareness.
A: Yes, we strictly adhere to a win-win, distributor-first channel policy:
Any direct inquiries, sample requests, or business leads received through our website or international trade shows from an authorized region will be precisely forwarded to our local exclusive or authorized distributor.
We protect your market efforts and actively help you convert local brand clients into long-term order.
A: We offer highly flexible logistical terms to support your business:
Minimum Order Quantity (MOQ): For most of our active ingredients, the MOQ is as low as 1 kg, allowing high flexibility for your inventory management.
Lead Time: Our standard lead time is highly competitive. Products are typically dispatched within 3 to 5 working days upon receipt of payment, subject to specific product availability and shipping logistics.
A: We maintain an open, strategic, and highly supportive attitude toward building exclusive global partnerships. We evaluate potential distributors based on:
Local distribution channels and market expertise.
Annual purchase volume projections.
Market expansion and promotional plans.
If you are interested in growing with us, please click the [Apply Now] to contact our business manager, and we will answer everything you would like to know.
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