Pro-Xylane

Plamed Vision: Become the leader of natural cosmetic ingredients for sensitive skin.

Pro-Xylane

  • No irritating odor, no toxicity, low content of acetic acid and borate, won’t affect the formulation.
  • Good water solubility and stability, not easy oxidation, easily absorbed by skin.
Plamed is the largest Pro-Xylane supplier in China with good Pro-Xylane price and high quality. Where to buy Pro-Xylane with reasonable price and high quality? Where to find good information of wholesale Pro-Xylane? As the professional Pro-Xylane manufacturer, Plamed is your best choice.

Pro-Xylane, also known as hydroxypropyl tetrahydropyrantriol, is a glycoprotein mixture derived from xylose. Since xylose exists in large quantities in beech trees, it has the ability to promote the production of glucosaminoglycans, namely mucopolysaccharides (GAGs). Also, xylose can provide binding sites for GAGs, start the generation and assembly of GAGs in the skin, and improve the deficiency of GAGs caused by skin aging. Studies have shown that Pro-Xylane is easy to biodegrade, does not accumulate in organisms, and has no toxicity.

Plamed develops 2 kinds of Pro-Xylane, 30% liquid and 98% powder. Both are water-soluble It can be used in skincare products for anti-aging.

Product Name CAS Number INCI Name
Pro-Xylane 439685-79-7 HYDROXYPROPYL TETRAHYDROPYRANTRIOL
Molecular Weight Molecular Formula Molecular Structure
192.21g/mol C8H16O5
Product ID Specification Minimal Package Minimal Order Quantity
PMKZ2201 30% liquid 1kg 1kg
PMKZ2202 98% powder 1kg 1kg

The inventor of Pro-Xylane, Dr. Maria DALKO-CSIBA, a scientist at the L’Oreal R&D and Innovation Center, is based on this characteristic of xylose, using a large number of beech and birch trees that exist in nature. In 1999-2000, he led the team to synthesize more than 200 kinds of xylose derivatives. Based on comprehensive consideration of factors such as efficacy, safety, stability and skin bioavailability, Pro-Xylane was finally successfully screened out. Nowadays, Pro-Xylane mainly obtained by chemical synthesis.

98% Powder Specification

Items Specification
Purity ≥99% HPLC
Appearance White to off-white powder
Odor Characteristic
Physical Characteristics
Loss on drying ≤3.0%
pH (10% water solution) 4.0-8.0
Heavy Metals
Pb ≤10ppm
As ≤2ppm
Hg ≤1ppm
Cd ≤5ppm
Microbiological Tests
Total plate count ≤1000cfu/g
Yeast & mold ≤100cfu/g
Pseudomonas aeruginosa Negative
Staphylococcus aureus Negative
Heat-resistant escherichia coli Negative
  • Anti-aging

Studies have proved that Pro-Xylane can exert biological effects at different layers of the skin

  • Acting on the epidermis, Pro-Xylanecan promote the synthesis of various GAGs, and at the same time up-regulate the expression of hyaluronic acid receptor CD44 and syndecan, thereby activating the signal pathway mediated by GAGs. Clinical studies have shown that topical application of Pro-Xylane can effectively reduce transepidermal water loss, improve skin barrier function, and promote epidermal renewal, making the skin plump and radiant.

  • At the Dermal-Epidermal Junction (DEJ), Pro-Xylanecan up-regulate collagen type IV (the main component of the lamina densa), laminin, type VII collagen (the main component of anchoring fibrils) and other key proteins. Then it can induce the expression of proteoglycanperlecan, and strengthen the tightness and stability of DEJ structure. Clinical studies have shown that in aging skin samples, the ultra-microscopic structure of DEJ presents the aging characteristics in several areas. After local application of Pro-Xylane, the DEJ structure of aging skin can be made more uniform and clear, the re-duplication of lamina densa is significantly reduced, making the skin structure stronger.

  • In the dermis, Pro-Xylanecan promote the production of various GAGs such as hyaluronic acid and heparan sulfate. In addition, the up-regulation of the expression of type I procollagen and fibrillin-1 is observed, suggesting that the production of GAGs and collagen. They are both important dermal extracellular matrix components that maintain skin elasticity and firmness. Therefore, it has been proved in clinical research that topical application of Pro-Xylane can effectively improve the fine lines and wrinkles of the skin, and make the skin firm and elastic.
  • Skin Repair

In vitro skin experiments, Pro-Xylane is able to reconstruct the complete structure of the epidermodermal layer, and it also had similar function as retinoic acid, enhancing the thickness of the stratum corneum and providing barrier function, but without irritation.

Pro-Xylane is mainly used in anti-aging, skin repair, anti-wrinkle skincare products, such as serum, facial mask, emulsion, toner, essence, cream, etc.

Product Reference Dosage
30% Pro-Xylane 0.2%-3% in leave-on cosmetics
0.3-5% in wash-off cosmetics
98% Pro-Xylane 0.5%-2%

Pro-Xylane application cases in major cosmetic brands in the world:

Brand Product
L’Oreal RevitaLift Triple Power Eye Treatment

Revitalift Triple Power Intensive Anti-Aging Moisturizer

SkinCeuticals  Hyaluronic Acid Intensifier Hydrating Serum

A.G.E. Interrupter Moisturizer

Biotherm Homme Force Supreme Lotion
La Roche-Posay Substiane Serum

Substiane [+] UV SPF 15

Hyalu B5 Hyaluronic Acid Eye Cream

Estee Lauder  RE-NUTRIV Ultimate Lift Regenerating Youth Serum
LANCOME Absolue demaquillant gel

ABSOLUE L’EXTRAIT ULTIMATE EYE CONTOUR COLLECTION

ABSOLUE REVITALIZING EYE SERUM

Absolue White Aura

KIEHL’S Hydrating & Clarifying Treatment Masque

KIEHL’S Clearly corrective dark spot solution

Vichy Neovadiol Compensating Complex Night Cream

Neovadiol complexe substitutif day cream

IDEALIA DAY CARE

  • CTFAhas recognized HYDROXYPROPYL TETRAHYDROPYRANTRIOL as a raw material for cosmetics;
  • The International Catalogue of Chinese Cosmetic Raw Materials Standardsin 2018 issued by HYDROXYPROPYL TETRAHYDROPYRANTRIOL.
  • On the Announcement of Name List of Cosmetics Raw Materialpublished by CFDA in 2021 both include HYDROXYPROPYL TETRAHYDROPYRANTRIOL.

Package: 1kg/bag, 1kg/bottle

Storage: Store in cool and dry place at room temperature, keep away from strong light.

Q1: What quality certifications do your cosmetic ingredients hold?

A: To meet strict global standards and diverse market needs, our cosmetic ingredients are certified under major international systems:

ISO 9001:2015 (Quality Management System): Guarantees that our manufacturing processes—from raw material sourcing to final production—adhere to strict quality control standards. Ensures consistent batch-to-batch stability, which is essential for our clients in the Europe and US markets looking for premium, compliant, and reliable supply chains.

Halal Certification: Fully certified Halal, ensuring compliance with strict ingredient traceability and the absence of prohibited substances or cross-contamination.

Allows our partners to seamlessly enter and expand in the Southeast Asian (e.g., Indonesia, Malaysia) and Middle Eastern markets, meeting local regulatory mandates.

We are committed to providing fully traceable, high-quality, and compliant ingredients to support your brand’s global growth. If you need copies of our certificates or specific technical documentation (such as COA, MSDS, or compliance statements), please feel free to contact our team.

Q2: Are your active ingredients compliant with regulations in the EU, US, and South Korea?

A: Yes, absolutely. Regulatory compliance and safety are our top priorities. All of our premium active ingredients have standard, internationally recognized INCI names and are fully compliant with the stringent regulations of these major markets:

European Union: Fully compliant with the EU Cosmetic Regulation (EC) No 1223/2009, including safety assessments, and banned/restricted substance lists.

United States: Formulated and manufactured in strict accordance with FDA guidelines and the latest MoCRA (Modernization of Cosmetics Regulation Act) requirements, ensuring smooth product registration and listing.

South Korea: Compliant with the regulations set by the MFDS (Ministry of Food and Drug Safety), meeting their strict standards for functional cosmetic ingredients and efficacy documentation.

Whether you are a distributor or a brand owner in Europe, the Americas, or Southeast Asia, you can seamlessly integrate our ingredients into your formulations. We provide comprehensive regulatory support dossiers (COA, TDS, MSDS, and Composition Statements) to facilitate your local product promotion.

Q3: Do you provide clinical data to support the efficacy of your ingredients?

A: Yes, we provide comprehensive efficacy dossiers for all our flagship ingredients (such as PMSoothe® Kava97, PCR® Supermolecule Escin, and PMRefresh® Willow). Our data packages include:

In-vitro (cell-based) test reports to demonstrate cellular-level activihttphttp://zhitiye.com/product/anti-irritating-cosmetics-ingredient-pmsoothe-kava97/://zhitiye.com/product/anti-irritating-cosmetics-ingredient-pmsoothe-kava97/ty and pathways.

In-vivo (human clinical) trial data to prove real-world visible results.

Safety assessments and clear Mechanism of Action (MOA) diagrams.

These rigorous, science-backed materials are designed to help our distributors easily convince formulation chemists and premium brand owners.

Q4: Can we request free samples for lab testing? Do you provide formulation support?

A: Absolutely. We support our partners’ R&D efforts through a two-step support system:

Free Samples: We provide complimentary samples for laboratory evaluation and pilot trials.

Technical & Formulation Support: To accelerate your application process, we will also provide formulation guides for you.

Our dedicated technical support team is also available to help your customers resolve challenges related to formulation stability, compatibility, and optimal dosage.

Q5: What marketing and sales support do you offer to international distributors?

A: We empower our global distributors with a comprehensive suite of “Turn-key” Marketing Kits to minimize your promotional costs and time-to-market. Our support includes:

Technial Documentation: Product brochures, white papers, and TDS, MSDS, and COA.

Visual Materials: Ingredient videos and ready-to-use social media posters.

Market Intelligence: Detailed competitive analysis reports and trend insights.

Co-Marketing: We also attend at major international cosmetics exhibitions to boost local brand awareness.

Q6: Do you pass customer leads or regional inquiries to your distributors?

A: Yes, we strictly adhere to a win-win, distributor-first channel policy:

Any direct inquiries, sample requests, or business leads received through our website or international trade shows from an authorized region will be precisely forwarded to our local exclusive or authorized distributor.

We protect your market efforts and actively help you convert local brand clients into long-term order.

Q7: What is the Minimum Order Quantity (MOQ) and lead time for international shipping?

A: We offer highly flexible logistical terms to support your business:

Minimum Order Quantity (MOQ): For most of our active ingredients, the MOQ is as low as 1 kg, allowing high flexibility for your inventory management.

Lead Time: Our standard lead time is highly competitive. Products are typically dispatched within 3 to 5 working days upon receipt of payment, subject to specific product availability and shipping logistics.

Q9: How to be Plamed’s exclusive distributor?

A: We maintain an open, strategic, and highly supportive attitude toward building exclusive global partnerships. We evaluate potential distributors based on:

Local distribution channels and market expertise.

Annual purchase volume projections.

Market expansion and promotional plans.

If you are interested in growing with us, please click the [Apply Now] to contact our business manager, and we will answer everything you would like to know.

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