Plamed Vision: Become the leader of natural cosmetic ingredients for sensitive skin.
Ferulic Acid is a premium active ingredient series developed by Plamed Green Science Group. Derived from natural botanical sources, the products are standardized for highly purified actives and designed to target specific skincare concerns through advanced formulation science.
| Product Name | CAS Number | INCI Name | |
| Ferulic Acid | 1135-24-6 | Ferulic Acid | |
| Molecular Weight | Molecular Formula | Molecular Structure | |
| 194.19g/mol | C10H10O4 |  | |
| Product ID | Specificcation | Minimal Package | Minimal Order Quantity |
| PMFS0301 | Natural source 99% Synthesis 99% | 1KG | 1KG |
Plamed develops natural Ferulic Acid and synthetic Ferulic Acid. Both of them are cosmetic grade raw materials, which can provide customers with different choice.
| Natural source | Chemical synthetic source | |
| Raw material | Rice bran | Vanillin and malonic acid |
| Specific process | Hydrolyze oryzanol (alcohol extract of rice bran) by sodium hydroxide or potassium hydroxide under 90-100℃ for 8h, then add sulfuric acid to adjust pH value to acidity, Ferulic Acid is precipitated. | Use anhydrous pyridine as solvent and piperidine as catalyst, then obtain Ferulic Acid by condensation reaction. |
| Advantage | The product obtained by this method is Cis-Ferulic Acid with high purity. The process is simple; the raw material is easy to get; the comprehensive benefit is high. | Raw materials are readily available; less expensive than natural sources. |
| Disadvantage | / | Ferulic acid obtained by this method is a mixture of Cis-Ferulic Acid And Trans-Ferulic Acid. Reaction time is long (up to 3 weeks); large solvent consumption, and low yield. |
| Product Name | Specification |
| Ferulic Acid | Natural source 99% Synthesis 99% |
Natural Ferulic Acid Specification
| Items | Specifications |
| Assay | ≥99% HPLC |
| Appearance | White or off-white color powder |
| Odor | Characteristic |
| Extract solvent | Water & ethanol |
| Physical Characteristics | |
| Moisture | ≤0.5% |
| Melting point | 170.0℃~174.0℃ |
| Natural degree c13 test | -33~36 |
| Natural degree C14/12test | 12-16 |
| Solvent residue | Ethanol≤1000ppm |
Synthetic Ferulic Acid Specification
| Items | Specifications |
| Assay | ≥99% |
| Appearance | White or yellowish needle-shaped crystal |
| Physical Characteristics | |
| Melting point | 172.0~175.0℃ |
| Moisture | ≤0.5% |
| Ash content | ≤0.1% |
| Heavy Metals | |
| Heavy metals | ≤10ppm |
| Related impurities | |
| Unspecified impurities | ≤0.1% |
| Total impurities | ≤0.5% |
Ferulic Acid, as a phenolic plant ingredient, can form relatively stable free radicals due to its conjugate system. Then it plays the role of stopping the free radical chain transfer in the automatic oxidation process of lipids. Therefore, Ferulic Acid has strong antioxidant activity, and can scavenge free radicals. Studies have shown that Ferulic Acid has a strong scavenging effect on DPPH free radicals, hydroxyl radicals and superoxide anions. Half inhibitory concentrations are 0.552mg /mL, 0.282mg /mL and 0.111mg /mL respectively. Ferulic Acid can also promote the production of free radical scavenging enzymes to achieve its anti-oxidative effect. It promotes the production of glutathione and NADP. When used in combination with vitamin C and vitamin E, it increases their stability and doubles their antioxidant capacity.
Ferulic Acid can inhibit tyrosinase activity. It can reduce the proliferation activity of melanocytes. Test result shows that when use 0.1-0.5% Ferulic Acid solution, the number of melanocytes decreases from 117±23/mm2 to 39±7/mm2. The inhibition rate of tyrosinase is up to 86%, when use 5mmol/L Ferulic Acid solution. Therefore, Ferulic Acid can whiten skin and remove spots. It has great whitening effect.
Ferulic Acid has good sun protection function. It can effectively absorb the ultraviolet rays in the wavelength range of 290~330nm. Thereby it prevents or reduces skin damage caused by the ultraviolet rays. (The UV rays in the range of 305-310nm are most likely to induce the skin erythema).
| Test Item | Concentration | Result |
| Elimination of free radical DPPH | Half elimination quantity EC50: 0.226mg/mL | |
| Elimination of superoxide free radicals | Half elimination quantity EC50: 0.530 mg/mL | |
| Elimination of hydroxyl radicals | Half elimination quantity EC50: 0.283mg/mL | |
| Inhibition of lipid peroxidation | 12.5mmol/L | Inhibition rate: 67.8% |
| Promotion of collagen production by culture of human dermal fibroblasts | 0.08% | Promotion rate: 716.7（blank 100） |
| Promotion of keratinocytes proliferation by cell culture | 10ug/mL | Promotion rate: 234（blank 100） |
| Inhibition of tyrosinase activity | 0.5mmol/L | Inhibition rate: 53.9% |
| Inhibition of cyclooxygenase-2 activity | Half inhibition quantity IC50: 10umol/L | |
| Inhibition of interleukin -4 production | 4umol/L | Inhibition rate: 18.2% |
| Inhibition of mast cell activity | 4umol/L | Inhibition rate: 14.5% |
| Product | Reference Dosage |
| Ferulic Acid 99% | 0.3%-2.0% |
Attention:
Ferulic Acid application cases in major cosmetic brands in the world:
| Country | Brand | Product |
| China | Chando | Cellcrystal Whitening Emulsion, Crystal White Deeply Essence, Aging Resistance White Spot Corrector, Snow Whitening Lotion |
| Genuine Namir | Snow Rose Crystal Whitening Essence | |
| Korea | Su:m 37º | Secret Essence, Bright award Micro Whipping Deep Cleansing Foam |
| USA | Elizabeth Arden | Prevage City Smart Spf50 Hydrating Shield, Mad Hippie Hydrating Nutrient Mist, Prevage Anti-Aging Antioxidant Infusion Essence |
| KIEHL‘S CILANTRO | Orange Extract Pollutant Defending Masque | |
| Estee Lauder | Re-Nutriv Re-Creation Night Creme | |
| France | LA ROCHE-POSAY | Sensi White Eye Cream, Pigmentclar Serum |
| Lancome | Advanced Genifique |
Whitening emulsion：
| Ingredient | Content（%） | Ingredient | Content（%） |
| Ferulic Acid | 0.5 | BHT | 0.01 |
| Monoglyceride | 10.0 | Butylparaben | 0.1 |
| Liquid paraffin | 10.0 | Propylene glycol | 10.0 |
| Mineral oil | 4.0 | Polyoxyethylene 20 cetyl ether | 2 |
| Cetyl alcohol | 5.0 | γ- tocopherol | 0.05 |
| Refined water | Add to 100 | ||
Skin care gel:
| Ingredient | Content（%） | Ingredient | Content（%） |
| Ferulic Acid | 0.5 | Lecithin | 6.0 |
| Shea butter | 3.0 | Chrysin | 0.1 |
| Vitamin A palmitate | 0.2 | Vitamin H | 0.08 |
| Sodium citrate | 0.5 | Glycerin | 0.2 |
| Carbamide | 0.2 | Sodium dichloroacetate | 0.5 |
| Hydrolyzed collagen | 2.0 | Xanthan gum | 1.4 |
| Sorbitol | 3.0 | Preservative | Appropriate |
| Refined water | Add to 100 | ||
Skin care emulsion:
| Ingredient | Content（%） | Ingredient | Content（%） |
| Ferulic Acid | 0.25 | Liquid paraffin | 20.0 |
| Paraffin | 4.0 | Glucose sesquistearate | 2.0 |
| Aluminium stearate | 0.4 | Naringin | 1.0 |
| Vitamin E acetate | 2.0 | Ascorbyl Palmitate | 0.1 |
| Glycerin | 5.0 | Preservative | Appropriate |
| Refined water | Add to 100 | ||
Skin care cream:
| Ingredient | Content（%） | Ingredient | Content（%） |
| Ferulic Acid | 1.0 | Squalane | 10 |
| Isopropyl myristate | 7.0 | Docosanol | 1.0 |
| Cetyl alcohol | 5.5 | Glycerin monostearate | 2.0 |
| D-α- tocopherol | 0.05 | POE(20) Sorbitan monostearate | 2.0 |
| Xanthan gum | 0.1 | 1,3 butanedio | 2.0 |
| Glycerin | 3.0 | Sorbitol | 5.0 |
| Activator | 0.2 | Ph regulator | Appropriate |
| Refined water | Add to 100 | ||
Shampoo：
| Ingredient | Content（%） | Ingredient | Content（%） |
| Ferulic Acid | 1.5 | Triethanolamine | 3.5 |
| Propylene glycol | 15.0 | Menthol | 0.1 |
| Ethanol | 15.0 | Polyoxyethylene hydrogenated castor oil | 0.5 |
| NSAIDs | 1.0 | Fragrance | 0.3 |
| Refined water | 65.1 | ||
Package: Packed in 25kg paper drums with two plastic bags inside.
Storage: Stored in a cool dry place and away from direct sunlight and oxidizing agents.
